Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases

Joint Authors

Dai, Yunkai
Zhang, Yunzhan
Chen, Weijing
Hu, Ling
Chen, Xu
Gong, Lin
Li, Danyan
Lan, Shaoyang
Luo, Qi
Chen, Bin
Li, Ruliu

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-02-12

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Medicine

Abstract EN

H.

pylori-related gastric diseases (HPGD) are a series of gastric mucosal benign and malignant lesions associated with H.

pylori infection.

Exploring the pathogenesis of HPGD will be of great significance to prevent and treat gastric malignancy.

Traditional Chinese medicine (TCM) syndrome is the essence of TCM, reflecting the state of whole body.

Potential similarities of TCM syndrome may provide a new perspective in understanding development and treatment of diseases.

To seek an early warning signal for gastric malignant pathology and similarities of TCM syndrome from the viewpoint of molecular biology, we examined the relationships among H.

pylori, gastric pathology, and TCM syndrome and effects of Interleukin-1β (IL-1β) gene polymorphisms and expression on gastric pathology and TCM syndrome in HPGD.

The results indicated that detection of H.

pylori with differentiation of TCM syndrome may have a predictive function to gastric pathology.

H.

pylori may lead to gastric atrophy via enhancing IL-1β mRNA expression, and IL-1β mRNA overexpression in gastric mucosa may be one of the generality characteristics for H.

pylori-negative subjects with syndrome of dampness-heat in the spleen and stomach.

American Psychological Association (APA)

Zhang, Yunzhan& Chen, Xu& Gong, Lin& Li, Danyan& Dai, Yunkai& Lan, Shaoyang…[et al.]. 2020. Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1156934

Modern Language Association (MLA)

Zhang, Yunzhan…[et al.]. Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1156934

American Medical Association (AMA)

Zhang, Yunzhan& Chen, Xu& Gong, Lin& Li, Danyan& Dai, Yunkai& Lan, Shaoyang…[et al.]. Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1156934

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1156934