Prognostic Value of Combination of Pretreatment Red Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio in Patients with Gastric Cancer
Joint Authors
Liu, Tao
Zhang, Tao
Wu, Ying
Zhou, Danyang
Lin, Zhenyu
Shi, Liangliang
Zhao, Lei
Yu, Dandan
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aims.
Gastric cancer (GC) is often diagnosed at an advanced stage; inexpensive and valid biomarkers for GC are still unavailable.
We aimed to evaluate the prognosis of the combination of pretreatment red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) in patients with GC.
Methods.
A retrospective analysis from 103 GC patients who were diagnosed at our institution from 2012 to 2016 was performed.
Both pretreatment RDW and NLR were calculated based on the recommended cutoff values of 13.4% and 2.755, respectively.
Combined values of RDW and NLR (RDW + NLR) stratified patients into a score of 0 (RDW ≤ 13.4% and NLR ≤ 2.755), a score of 1 (RDW > 13.4% or NLR > 2.755), and a score of 2 (RDW > 13.4% and NLR > 2.755).
Prognostic significances for overall survival (OS) and progression-free survival (PFS) were assessed.
Results.
Pretreatment RDW + NLR was a significantly independent prognostic factor for OS and PFS.
Moreover, high RDW + NLR was strongly related to age, tumor location, TNM stage, CA125, and CA199.
In a subgroup analysis for patients with advanced gastric cancer (AGC), we observed that the level of RDW + NLR was markedly associated with OS and PFS.
Conclusion.
Pretreatment RDW + NLR is a simple, inexpensive, and valid prognostic system to predict the survival in patients with GC, especially AGC.
American Psychological Association (APA)
Zhou, Danyang& Wu, Ying& Lin, Zhenyu& Shi, Liangliang& Zhao, Lei& Liu, Tao…[et al.]. 2018. Prognostic Value of Combination of Pretreatment Red Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio in Patients with Gastric Cancer. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1165644
Modern Language Association (MLA)
Zhou, Danyang…[et al.]. Prognostic Value of Combination of Pretreatment Red Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio in Patients with Gastric Cancer. Gastroenterology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1165644
American Medical Association (AMA)
Zhou, Danyang& Wu, Ying& Lin, Zhenyu& Shi, Liangliang& Zhao, Lei& Liu, Tao…[et al.]. Prognostic Value of Combination of Pretreatment Red Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio in Patients with Gastric Cancer. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1165644
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165644