Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China
Joint Authors
Lu, Yingli
Xia, Fangzhen
Cheng, Jing
Han, Bing
Li, Qin
Zhai, Hualing
Wang, Ningjian
Jensen, Michael
Source
International Journal of Endocrinology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The strength of associations between total testosterone (TT) and metabolic parameters may vary in different nature of population structure; however, no study has ever given this information in Chinese population, especially those without metabolic syndrome (MS).
We aimed to analyze the association magnitudes between TT and multiple metabolic parameters in general Chinese men.
Methods.
4309 men were recruited from SPECT-China study in 2014-2015, which was performed in 22 sites in East China.
TT, weight status, and various metabolic parameters were measured.
Linear and logistic regressions were used to analyze the associations.
Results.
Men in lower TT quartiles had worse metabolic parameters including body mass index, triglycerides, HbA1c, and HOMA-IR (all P for trend < 0.001).
Body mass index (B −0.32, 95%CI −0.35 to −0.29) and obesity (OR 0.40, 95%CI 0.35–0.45) had the largest association magnitude per one SD increment in TT, while blood pressure and hypertension (OR 0.90, 95%CI 0.84–0.98) had the smallest.
These associations also persisted in individuals without metabolic syndrome.
Conclusions.
Obesity indices had closer relationships with TT than most other metabolic measures with blood pressure the least close.
These associations remained robust after adjustment for adiposity and in subjects without metabolic syndrome.
American Psychological Association (APA)
Cheng, Jing& Han, Bing& Li, Qin& Xia, Fangzhen& Zhai, Hualing& Wang, Ningjian…[et al.]. 2017. Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1166210
Modern Language Association (MLA)
Cheng, Jing…[et al.]. Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China. International Journal of Endocrinology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1166210
American Medical Association (AMA)
Cheng, Jing& Han, Bing& Li, Qin& Xia, Fangzhen& Zhai, Hualing& Wang, Ningjian…[et al.]. Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1166210
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166210