Prognostic Value of the Pretreatment Systemic Immune-Inflammation Index in Patients with Colorectal Cancer
Joint Authors
Qian, Hongyan
Shao, Jingjing
Zhao, Wenjing
Zhang, Xunlei
Cui, Xiaopeng
Jiang, Xiaohui
Li, Jing
Chen, Xin
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Multiple studies have reported the significance of the systemic immune-inflammation index (SII) in the prognosis of colorectal cancer (CRC), but no consensus has yet been reached.
The purpose of this study was to systematically assess the prognostic value of SII in patients with CRC.
Materials and Methods.
We performed a systematic literature search in PubMed, Embase, and the Cochrane Library for eligible studies.
The correlation between pretreatment SII and overall survival (OS), disease-free survival (DFS), and progression-free survival (PFS) in CRC patients was evaluated by combining the hazard ratio (HR) and 95% confidence interval (CI).
Results.
Twelve studies involving 3919 patients were included.
Comprehensive analysis results showed that high SII indicated poor OS in CRC patients (HR=1.777, 95% CI: 1.328-2.376).
Compared with patients with low SII values, patients with high SII had lower PFS (HR=1.658, 95% CI: 1.189-2.311).
Subgroup analysis further verified the above results.
Conclusions.
SII may be a noninvasive and powerful tool for predicting survival outcomes in CRC patients.
However, more well-designed studies are needed to validate our findings.
American Psychological Association (APA)
Li, Jing& Shao, Jingjing& Zhang, Xunlei& Chen, Xin& Zhao, Wenjing& Qian, Hongyan…[et al.]. 2020. Prognostic Value of the Pretreatment Systemic Immune-Inflammation Index in Patients with Colorectal Cancer. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167073
Modern Language Association (MLA)
Li, Jing…[et al.]. Prognostic Value of the Pretreatment Systemic Immune-Inflammation Index in Patients with Colorectal Cancer. Gastroenterology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1167073
American Medical Association (AMA)
Li, Jing& Shao, Jingjing& Zhang, Xunlei& Chen, Xin& Zhao, Wenjing& Qian, Hongyan…[et al.]. Prognostic Value of the Pretreatment Systemic Immune-Inflammation Index in Patients with Colorectal Cancer. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167073
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167073