A Simple and Rapid Method for Quantitative HPLC MSMS Determination of Selected Perfluorocarboxylic Acids and Perfluorosulfonates in Human Serum
Joint Authors
Marra, Valentina
Abballe, Annalisa
Dellatte, Elena
Iacovella, Nicola
Ingelido, Anna Maria
De Felip, Elena
Source
International Journal of Analytical Chemistry
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Per- and polyfluorinated alkyl substances (PFASs) are ubiquitous environmental contaminants, present in the environment and in the human body.
They have raised global concern because of their diffusion in the environment, particularly in water, causing cases of human overexposure due to consumption of contaminated drinking water.
Human biomonitoring is the most effective way to characterize human exposure to PFASs, and it is important that as many labs as possible could easily perform this kind of analysis.
Analytical methods for quantitation of PFAS mixtures in human serum have been developed, but most of them required materials that are not always easily available in all the laboratories.
This paper describes a very simple and accessible HPLC MS/MS method of analysis and quantification of 13 perfluorocarboxylic acids and perfluorosulfonate compounds (belonging to the class of per- and polyfluorinated alkyl substances (PFASs)) in human serum.
Method development data provide detailed descriptions of the optimization process in terms of sample preparation, laboratory analysis of human serum samples, determination of analytes by HPLC MS/MS, and describing the pump gradient time, working conditions, and acquisition.
American Psychological Association (APA)
Marra, Valentina& Abballe, Annalisa& Dellatte, Elena& Iacovella, Nicola& Ingelido, Anna Maria& De Felip, Elena. 2020. A Simple and Rapid Method for Quantitative HPLC MSMS Determination of Selected Perfluorocarboxylic Acids and Perfluorosulfonates in Human Serum. International Journal of Analytical Chemistry،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1167798
Modern Language Association (MLA)
Marra, Valentina…[et al.]. A Simple and Rapid Method for Quantitative HPLC MSMS Determination of Selected Perfluorocarboxylic Acids and Perfluorosulfonates in Human Serum. International Journal of Analytical Chemistry No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1167798
American Medical Association (AMA)
Marra, Valentina& Abballe, Annalisa& Dellatte, Elena& Iacovella, Nicola& Ingelido, Anna Maria& De Felip, Elena. A Simple and Rapid Method for Quantitative HPLC MSMS Determination of Selected Perfluorocarboxylic Acids and Perfluorosulfonates in Human Serum. International Journal of Analytical Chemistry. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1167798
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167798