Prevalence, Response to Cysticidal Therapy, and Risk Factors for Persistent Seizure in Indian Children with Neurocysticercosis
Joint Authors
Singh, Amitabh
Kumar, Animesh
Mandal, Anirban
Sinha, Sheela
Das, Rashmi Ranjan
Source
International Journal of Pediatrics
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Neurocysticercosis (NCC) is the commonest cause of childhood acquired epilepsy in developing countries.
The use of cysticidal therapy in NCC, except “single lesion NCC,” is still debated in view of its doubtful usefulness and potential adverse effects.
Methods.
Children presenting with first episode of seizure or acute focal neurological deficit without fever were screened for NCC and received appropriate therapy (followup done for 1 year to look for the response and side effects).
Results.
The prevalence of NCC was 4.5%.
Most common presenting feature was generalized seizure and commonest imaging finding was single small enhancing lesion in the parietal lobe.
Abnormal EEG and CSF abnormalities were found in almost half of the children.
The response to therapy was very good with infrequent recurrence of seizure and adverse effects of therapy were encountered rarely.
No risk factors for persistent seizure could be identified.
Conclusion.
Present study shows that the response to cysticidal therapy is very good in NCC as seizure recurrence was observed in only 5%, 4.2%, and 4.2% of cases at 3-month, 6-month, and 1-year followup.
Adverse effects of therapy were observed in 20% of cases during therapy but they were mild and self-limiting.
American Psychological Association (APA)
Kumar, Animesh& Mandal, Anirban& Sinha, Sheela& Singh, Amitabh& Das, Rashmi Ranjan. 2017. Prevalence, Response to Cysticidal Therapy, and Risk Factors for Persistent Seizure in Indian Children with Neurocysticercosis. International Journal of Pediatrics،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1168726
Modern Language Association (MLA)
Kumar, Animesh…[et al.]. Prevalence, Response to Cysticidal Therapy, and Risk Factors for Persistent Seizure in Indian Children with Neurocysticercosis. International Journal of Pediatrics No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1168726
American Medical Association (AMA)
Kumar, Animesh& Mandal, Anirban& Sinha, Sheela& Singh, Amitabh& Das, Rashmi Ranjan. Prevalence, Response to Cysticidal Therapy, and Risk Factors for Persistent Seizure in Indian Children with Neurocysticercosis. International Journal of Pediatrics. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1168726
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1168726