Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis
Joint Authors
Ferguson, Polly
Zhao, Yongdong
Dedeoglu, Fatma
Lapidus, Sivia K.
Laxer, Ronald M.
Bradford, Miranda C.
Li, Suzanne C.
Source
International Journal of Rheumatology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background/Purpose.
Understanding the practices of pediatric rheumatologists in diagnosing and treating chronic nonbacterial osteomyelitis (CNO) can provide important information to guide the development of consensus treatment plans.
The objectives of this study were to determine physicians’ approaches to (1) diagnosing and monitoring CNO, (2) ordering a bone biopsy, and (3) making treatment decisions.
Methods.
A survey was distributed among members of the Childhood Arthritis and Rheumatology Research Alliance using a web-based questionnaire.
Results.
121 of 277 (41%) attending physician members completed the survey.
Plain radiographs (89%) were most commonly used followed by regional MRI (78%), bone scintigraphy (43%), and whole-body MRI (36%).
The top three reasons for performing a biopsy were constitutional findings (66%), unifocal bone lesions (64%), and nocturnal bone pain (45%).
Nearly all responders (95%) prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) as initial therapy.
For patients who failed NSAID treatment, methotrexate (67%), tumor necrosis factor inhibitors (65%), and bisphosphonates (46%) were the next most commonly used treatments.
The presence of a spinal lesion increased the use of bisphosphonate treatment.
Conclusion.
The diagnostic approach and disease activity monitoring for CNO varied among surveyed physicians.
Our survey findings provided important background for the development of consensus treatment plans for CNO.
American Psychological Association (APA)
Zhao, Yongdong& Dedeoglu, Fatma& Ferguson, Polly& Lapidus, Sivia K.& Laxer, Ronald M.& Bradford, Miranda C.…[et al.]. 2017. Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis. International Journal of Rheumatology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1169382
Modern Language Association (MLA)
Zhao, Yongdong…[et al.]. Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis. International Journal of Rheumatology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1169382
American Medical Association (AMA)
Zhao, Yongdong& Dedeoglu, Fatma& Ferguson, Polly& Lapidus, Sivia K.& Laxer, Ronald M.& Bradford, Miranda C.…[et al.]. Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis. International Journal of Rheumatology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1169382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169382