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Synthesis of New Bis(spiro-β-lactams) via Interaction of Methyl 1-Bromocycloalcanecarboxylates with Zinc and N,N′-Bis(arylmethylidene)benzidines
Joint Authors
Kirillov, N. F.
Nikiforova, E. A.
Baibarodskikh, D. V.
Zakharova, T. A.
Govorushkin, L. S.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Interaction of the Reformatsky reagents, prepared from methyl 1-bromocyclopentane-1-carboxylate or methyl 1-bromocyclohexane-1-carboxylate, with N,N′-bis(arylmethylidene)benzidines has given rise to a set of intermediates as a result of nucleophilic addition to the C=N group of a substrate.
Further intramolecular attack of the amide nitrogen atom onto the ester carbonyl group is responsible for the ring closure, which affords two series of spirocompounds: 2,2′-([1,1′-biphenyl]-4,4′-diyl)bis(3-aryl-2-azaspiro[3.4]octan-1-one) or 2,2′-([1,1′-biphenyl]-4,4′-diyl)bis(3-aryl-2-azaspiro[3.5]nonan-1-ones).
American Psychological Association (APA)
Kirillov, N. F.& Nikiforova, E. A.& Baibarodskikh, D. V.& Zakharova, T. A.& Govorushkin, L. S.. 2019. Synthesis of New Bis(spiro-β-lactams) via Interaction of Methyl 1-Bromocycloalcanecarboxylates with Zinc and N,N′-Bis(arylmethylidene)benzidines. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1171641
Modern Language Association (MLA)
Kirillov, N. F.…[et al.]. Synthesis of New Bis(spiro-β-lactams) via Interaction of Methyl 1-Bromocycloalcanecarboxylates with Zinc and N,N′-Bis(arylmethylidene)benzidines. Journal of Chemistry No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1171641
American Medical Association (AMA)
Kirillov, N. F.& Nikiforova, E. A.& Baibarodskikh, D. V.& Zakharova, T. A.& Govorushkin, L. S.. Synthesis of New Bis(spiro-β-lactams) via Interaction of Methyl 1-Bromocycloalcanecarboxylates with Zinc and N,N′-Bis(arylmethylidene)benzidines. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1171641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171641