Association of HLA-B∗38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients

Joint Authors

Mai, Phuong-Thao
Do, Duc-Minh
Tuan, Pham Vo Anh
Linh, Le Gia Hoang
Van Hoang, Lam
Hen, Phan Huu
Hoa, Le Tuyet
Vu, Hoang Anh

Source

International Journal of Endocrinology

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-07-05

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Biology

Abstract EN

Background.

HLA-B∗38:02 has been shown to be associated with antithyroid drug-induced agranulocytosis in Asian patients.

Methods.

HLA-B∗38:02 was analyzed by sequence-based typing in 21 patients who developed antithyroid drug-induced agranulocytosis and in 81 controls.

Results.

Frequency of HLA-B∗38:02 was 52.4% in agranulocytosis patients compared to 3.7% in controls (OR = 28.6, 95% CI = 6.8–120.2).

Conclusions.

HLA-B∗38:02 is a significant risk factor for agranulocytosis in Kinh Vietnamese patients treated with antithyroid drug.

American Psychological Association (APA)

Mai, Phuong-Thao& Tuan, Pham Vo Anh& Linh, Le Gia Hoang& Van Hoang, Lam& Hen, Phan Huu& Hoa, Le Tuyet…[et al.]. 2018. Association of HLA-B∗38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1172098

Modern Language Association (MLA)

Mai, Phuong-Thao…[et al.]. Association of HLA-B∗38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients. International Journal of Endocrinology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1172098

American Medical Association (AMA)

Mai, Phuong-Thao& Tuan, Pham Vo Anh& Linh, Le Gia Hoang& Van Hoang, Lam& Hen, Phan Huu& Hoa, Le Tuyet…[et al.]. Association of HLA-B∗38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1172098

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1172098