Low, rather than High, Body Mass Index Is a Risk Factor for Acute Kidney Injury in Multiethnic Asian Patients: A Retrospective Observational Study
Joint Authors
Liu, Allen Yan Lun
Wang, Jiexun
Nikam, Milind
Lai, Boon Cheok
Yeoh, Lee Ying
Source
International Journal of Nephrology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-09
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Background.
Acute kidney injury (AKI) is common in hospitalised patients.
The relationship between body mass index (BMI) and the risk of having AKI for patients in the acute hospital setting is not known, particularly in the Asian population.
Methods.
This was a retrospective, single-centre, observational study conducted in Singapore, a multiethnic population.
All patients aged ≥21 years and hospitalised from January to December 2013 were recruited.
Results.
A total of 12,555 patients were eligible for the analysis.
A BMI of <18.5 kg/m2 was independently associated with the development of AKI in hospitalised patients (odds ratio (OR): 1.23 [95% confidence interval [CI]: 1.04–1.44, P=0.01]) but not for overweight and obesity.
Subgroup analysis further revealed that underweight patients aged ≥75 and repeated hospitalisation posed a higher risk of AKI (OR: 1.25 [CI: 1.01–1.56], P=0.04; OR: 1.23 [CI: 1.04–1.44], P=0.01, resp.).
Analyses by interactions between different age groups and BMI using continuous or categorised variables did not affect the overall probability of developing AKI.
Conclusions.
Underweight Asian patients are susceptible to AKI in acute hospital settings.
Identification of this novel risk factor for AKI allows us to optimise patient care by prevention, early detection, and timely intervention.
American Psychological Association (APA)
Liu, Allen Yan Lun& Wang, Jiexun& Nikam, Milind& Lai, Boon Cheok& Yeoh, Lee Ying. 2018. Low, rather than High, Body Mass Index Is a Risk Factor for Acute Kidney Injury in Multiethnic Asian Patients: A Retrospective Observational Study. International Journal of Nephrology،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1173607
Modern Language Association (MLA)
Liu, Allen Yan Lun…[et al.]. Low, rather than High, Body Mass Index Is a Risk Factor for Acute Kidney Injury in Multiethnic Asian Patients: A Retrospective Observational Study. International Journal of Nephrology No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1173607
American Medical Association (AMA)
Liu, Allen Yan Lun& Wang, Jiexun& Nikam, Milind& Lai, Boon Cheok& Yeoh, Lee Ying. Low, rather than High, Body Mass Index Is a Risk Factor for Acute Kidney Injury in Multiethnic Asian Patients: A Retrospective Observational Study. International Journal of Nephrology. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1173607
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173607