Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes
Joint Authors
Mauricio, Dídac
Alcubierre, Nuria
Rubinat, Esther
Cao, Gonzalo
Esquerda, Aureli
Granado-Casas, Minerva
Real, J.
Hernández, Marta
Fernández, Elvira
Ramírez-Morros, Anna
Martinez-Alonso, Montserrat
Castelblanco, Esmeralda
Alonso, Núria
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aims.
To assess whether circulating 25-hydroxyvitamin D3 (25OHD) and mineral metabolism-related factors (serum phosphate, calcium, and parathormone) are associated with subclinical carotid atherosclerosis (SCA), defined as the presence of carotid atherosclerotic plaques (main study outcome), in patients with type 2 diabetes mellitus (T2DM) without kidney disease or previous cardiovascular disease.
Methods.
We undertook a post hoc analysis of a cross-sectional study in adults with T2DM in whom we evaluated SCA.
A total of 303 subjects with T2DM were included.
Clinical variables and carotid ultrasound imaging were obtained.
Results.
We found no association of 25OHD with the presence of SCA.
However, calcium phosphate (CaP; mg2/dL2) product was positively associated with the presence of carotid plaques (ORadj = 1.078; 95% CI: 1.017–1.142).
An inverse association was observed between higher levels of 25OHD (≥30 ng/mL versus <20 ng/mL concentrations) and common carotid intima-media thickness (cIMT; mm) (βadj ± SE = −0.055 ± 0.024).
We conclude that the CaP product is independently associated with the presence of established subclinical carotid atherosclerosis in patients with T2DM.
American Psychological Association (APA)
Ramírez-Morros, Anna& Granado-Casas, Minerva& Alcubierre, Nuria& Martinez-Alonso, Montserrat& Real, J.& Castelblanco, Esmeralda…[et al.]. 2017. Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1174177
Modern Language Association (MLA)
Ramírez-Morros, Anna…[et al.]. Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes. Journal of Diabetes Research No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1174177
American Medical Association (AMA)
Ramírez-Morros, Anna& Granado-Casas, Minerva& Alcubierre, Nuria& Martinez-Alonso, Montserrat& Real, J.& Castelblanco, Esmeralda…[et al.]. Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1174177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174177