Antidiabetic Drugs in Alzheimer’s Disease: Mechanisms of Action and Future Perspectives
Joint Authors
Rengo, Giuseppe
De Lucia, Claudio
Femminella, Grazia Daniela
Bencivenga, Leonardo
Petraglia, Laura
Visaggi, Lucia
Gioia, Lucia
Grieco, Fabrizio Vincenzo
Komici, Klara
Edison, Paul
Ferrara, Nicola
Corbi, Graziamaria
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Diabetes mellitus (DM) and Alzheimer’s disease (AD) are two highly prevalent conditions in the elderly population and major public health burden.
In the past decades, a pathophysiological link between DM and AD has emerged and central nervous system insulin resistance might play a significant role as a common mechanism; however, other factors such as inflammation and oxidative stress seem to contribute to the shared pathophysiological link.
Both preclinical and clinical studies have evaluated the possible neuroprotective mechanisms of different classes of antidiabetic medications in AD, with some promising results.
Here, we review the evidence on the mechanisms of action of antidiabetic drugs and their potential use in AD.
American Psychological Association (APA)
Femminella, Grazia Daniela& Bencivenga, Leonardo& Petraglia, Laura& Visaggi, Lucia& Gioia, Lucia& Grieco, Fabrizio Vincenzo…[et al.]. 2017. Antidiabetic Drugs in Alzheimer’s Disease: Mechanisms of Action and Future Perspectives. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1174704
Modern Language Association (MLA)
Femminella, Grazia Daniela…[et al.]. Antidiabetic Drugs in Alzheimer’s Disease: Mechanisms of Action and Future Perspectives. Journal of Diabetes Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1174704
American Medical Association (AMA)
Femminella, Grazia Daniela& Bencivenga, Leonardo& Petraglia, Laura& Visaggi, Lucia& Gioia, Lucia& Grieco, Fabrizio Vincenzo…[et al.]. Antidiabetic Drugs in Alzheimer’s Disease: Mechanisms of Action and Future Perspectives. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1174704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174704