Determination of β-Agonist Residues in Animal-Derived Food by a Liquid Chromatography-Tandem Mass Spectrometric Method Combined with Molecularly Imprinted Stir Bar Sorptive Extraction
Joint Authors
Shi, Shuyun
Tang, Jiwang
Wang, Jianxiu
Hu, Shengqiang
Yuan, Liejiang
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
A novel clenbuterol molecularly imprinted polymer (MIP)-coated stir bar was prepared and applied to the determination of six β-agonists in animal-derived food.
Characterization and various parameters affecting adsorption and desorption behaviours were investigated.
The extraction capacities of clenbuterol, salbutamol, ractopamine, mabuterol, brombuterol, and terbutaline for MIP coating were 3.8, 2.9, 3.1, 3.5, 3.2, and 3.3 times higher, respectively, than those of the NIP coating, respectively.
The method of MIP-coated SBSE coupled with HPLC-MS/MS was developed.
The recoveries in pork and liver samples were 75.8–97.9% with RSD from 2.6 to 5.3%.
Limits of detection (LODs) and limits of quantification (LOQs) were 0.05–0.15 μg/kg and 0.10–0.30 μg/kg, respectively.
Good linearities were obtained for six β-agonists with correlation coefficients (R2) higher than 0.994.
These results indicated the superiority of the proposed method in the analysis of β-agonists in a complex matrix.
American Psychological Association (APA)
Tang, Jiwang& Wang, Jianxiu& Shi, Shuyun& Hu, Shengqiang& Yuan, Liejiang. 2018. Determination of β-Agonist Residues in Animal-Derived Food by a Liquid Chromatography-Tandem Mass Spectrometric Method Combined with Molecularly Imprinted Stir Bar Sorptive Extraction. Journal of Analytical Methods in Chemistry،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1176630
Modern Language Association (MLA)
Tang, Jiwang…[et al.]. Determination of β-Agonist Residues in Animal-Derived Food by a Liquid Chromatography-Tandem Mass Spectrometric Method Combined with Molecularly Imprinted Stir Bar Sorptive Extraction. Journal of Analytical Methods in Chemistry No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1176630
American Medical Association (AMA)
Tang, Jiwang& Wang, Jianxiu& Shi, Shuyun& Hu, Shengqiang& Yuan, Liejiang. Determination of β-Agonist Residues in Animal-Derived Food by a Liquid Chromatography-Tandem Mass Spectrometric Method Combined with Molecularly Imprinted Stir Bar Sorptive Extraction. Journal of Analytical Methods in Chemistry. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1176630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1176630