Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma

Author

Mishra, Amarjit

Source

Journal of Immunology Research

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-12-14

Country of Publication

Egypt

No. of Pages

12

Main Subjects

Biology

Abstract EN

Dendritic cells (DCs) are highly specialized in antigen presentation and play a pivotal role in the initiation, progression, and perpetuation of adaptive immune responses.

Emerging immune pathways are being recognized increasingly for DCs and their subsets that differentially regulate T lymphocyte function based on the type and interactions with the antigen.

However, these interactions not only alter the signaling process and DC function but also render metabolic plasticity.

The current review focuses on the metabolic cues of DCs that coordinate DC activation and differentiation and discuss whether targeting these fundamental cellular processes have implications to control airway inflammation and adaptive immunity.

Therefore, strategies using metabolism-based therapeutic manipulation of DC functions could be developed into novel treatments for airway inflammation and asthma.

American Psychological Association (APA)

Mishra, Amarjit. 2017. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1181894

Modern Language Association (MLA)

Mishra, Amarjit. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1181894

American Medical Association (AMA)

Mishra, Amarjit. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1181894

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1181894