Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma
Author
Source
Journal of Immunology Research
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Dendritic cells (DCs) are highly specialized in antigen presentation and play a pivotal role in the initiation, progression, and perpetuation of adaptive immune responses.
Emerging immune pathways are being recognized increasingly for DCs and their subsets that differentially regulate T lymphocyte function based on the type and interactions with the antigen.
However, these interactions not only alter the signaling process and DC function but also render metabolic plasticity.
The current review focuses on the metabolic cues of DCs that coordinate DC activation and differentiation and discuss whether targeting these fundamental cellular processes have implications to control airway inflammation and adaptive immunity.
Therefore, strategies using metabolism-based therapeutic manipulation of DC functions could be developed into novel treatments for airway inflammation and asthma.
American Psychological Association (APA)
Mishra, Amarjit. 2017. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1181894
Modern Language Association (MLA)
Mishra, Amarjit. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1181894
American Medical Association (AMA)
Mishra, Amarjit. Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1181894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181894