Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Chen, Jiang
Xiao-Zhong, Guo
Qi, Xingshun
Source
Journal of Immunology Research
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-07
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Specific immunotherapies, including vaccines with autologous tumor cells and tumor antigen-specific monoclonal antibodies, are important treatments for PC patients.
To evaluate the clinical outcomes of PC-specific immunotherapy, we performed a systematic review and meta-analysis of the relevant published clinical trials.
The effects of specific immunotherapy were compared with those of nonspecific immunotherapy and the meta-analysis was executed with results regarding the overall survival (OS), immune responses data, and serum cancer markers data.
The pooled analysis was performed by using the random-effects model.
We found that significantly improved OS was noted for PC patients utilizing specific immunotherapy and an improved immune response was also observed.
In conclusion, specific immunotherapy was superior in prolonging the survival time and enhancing immunological responses in PC patients.
American Psychological Association (APA)
Chen, Jiang& Xiao-Zhong, Guo& Qi, Xingshun. 2017. Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1182133
Modern Language Association (MLA)
Chen, Jiang…[et al.]. Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis. Journal of Immunology Research No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1182133
American Medical Association (AMA)
Chen, Jiang& Xiao-Zhong, Guo& Qi, Xingshun. Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1182133
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182133