Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population
Joint Authors
Mazidi, Mohsen
Gao, Hong-kai
Kengne, Andre Pascal
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and Aim.
The relationship between serum trans-fatty acids (TFAs) and systemic inflammation markers is unclear.
We investigated the association of serum TFAs with high sensitivity C-reactive protein (hs-CRP) and fibrinogen in adult Americans.
Methods.
The 1999 to 2000 National Health and Nutrition Examination Survey (NHANES) participants with measured data on hs-CRP and fibrinogen were included.
TFAs were measured via capillary gas chromatography and mass spectrometry using negative chemical ionization.
Analysis of covariance and multivariable-adjusted linear regression models were used to investigate the associations between these parameters, accounting for the survey design.
Results.
Of the 5446 eligible participants, 46.8% (n=2550) were men.
The mean age was 47.1 years overall: 47.8 years in men and 46.5 years in women (p=0.085).
After adjustment for age and sex, mean serum TFAs rose with the increasing quarters of hs-CRP and fibrinogen (both p<0.001).
In linear regression models adjusted for age, sex, race, education, marital status, body mass index, and smoking, serum TFAs were an independent predictor of plasma hs-CRP and fibrinogen levels.
Conclusion.
A high level of TFAs appears to be a contributor to an unfavourable inflammatory profile.
Because serum TFAs concentrations are affected by dietary TFA intake, these data suggest a possible contribution of TFAs intake modulation in the prevention of inflammation-related chronic diseases.
American Psychological Association (APA)
Mazidi, Mohsen& Gao, Hong-kai& Kengne, Andre Pascal. 2017. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183933
Modern Language Association (MLA)
Mazidi, Mohsen…[et al.]. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1183933
American Medical Association (AMA)
Mazidi, Mohsen& Gao, Hong-kai& Kengne, Andre Pascal. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183933
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183933