Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population

Joint Authors

Mazidi, Mohsen
Gao, Hong-kai
Kengne, Andre Pascal

Source

Journal of Nutrition and Metabolism

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-07-11

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Nutrition & Dietetics

Abstract EN

Background and Aim.

The relationship between serum trans-fatty acids (TFAs) and systemic inflammation markers is unclear.

We investigated the association of serum TFAs with high sensitivity C-reactive protein (hs-CRP) and fibrinogen in adult Americans.

Methods.

The 1999 to 2000 National Health and Nutrition Examination Survey (NHANES) participants with measured data on hs-CRP and fibrinogen were included.

TFAs were measured via capillary gas chromatography and mass spectrometry using negative chemical ionization.

Analysis of covariance and multivariable-adjusted linear regression models were used to investigate the associations between these parameters, accounting for the survey design.

Results.

Of the 5446 eligible participants, 46.8% (n=2550) were men.

The mean age was 47.1 years overall: 47.8 years in men and 46.5 years in women (p=0.085).

After adjustment for age and sex, mean serum TFAs rose with the increasing quarters of hs-CRP and fibrinogen (both p<0.001).

In linear regression models adjusted for age, sex, race, education, marital status, body mass index, and smoking, serum TFAs were an independent predictor of plasma hs-CRP and fibrinogen levels.

Conclusion.

A high level of TFAs appears to be a contributor to an unfavourable inflammatory profile.

Because serum TFAs concentrations are affected by dietary TFA intake, these data suggest a possible contribution of TFAs intake modulation in the prevention of inflammation-related chronic diseases.

American Psychological Association (APA)

Mazidi, Mohsen& Gao, Hong-kai& Kengne, Andre Pascal. 2017. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183933

Modern Language Association (MLA)

Mazidi, Mohsen…[et al.]. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1183933

American Medical Association (AMA)

Mazidi, Mohsen& Gao, Hong-kai& Kengne, Andre Pascal. Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population. Journal of Nutrition and Metabolism. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1183933

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1183933