Effect of Active and Passive Smoking on Retinal Nerve Fibre Layer and Ganglion Cell Complex
Joint Authors
Abdelmaguid Mohamed Elzankalony, Yasser
Farweez, Yousra Ahmed Thabet
Elewa, Lamia Salah
Farweez, Botheina Ahmed Thabet
El-Shazly, Amany Abdel-Fattah
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
To evaluate the possible structural and functional changes in the retinal nerve fibre layer (RNFL) and the ganglion cell complex (GCC) of chronic smokers and compare them with those of passive healthy smokers using spectral domain optical coherence tomography (SD-OCT) and pattern electroretinogram (PERG).
Materials and Methods.
We include 80 active chronic smokers and 80 age- and sex-matched healthy passive smokers.
After a full ophthalmological examination, SD-OCT and PERG were tested for all participants.
Urinary levels of cotinine and creatinine with subsequent calculation of the cotinine creatinine ratio (CCR).
Results.
Inferior and superior quadrants of RNFL were thinner in group I, but nasal and temporal quadrants did not show significant difference between the groups.
There were no significant differences of GCC values between the two groups.
There was no significant difference of PERG-P50 amplitude and latency; however, PERG-N95 showed significant difference between the two groups.
Multiple regression analyses demonstrated that the number of cigarettes/day, urinary cotinine, and PERG-N95 amplitude are the most important determinants for both superior and inferior RNFL thicknesses.
Conclusion.
RNFL thickness decreases in chronic, healthy, heavy cigarette smokers, and this thinning is related to the number of cigarettes/day, urinary cotinine, and PERG-N95 latency and amplitude.
American Psychological Association (APA)
El-Shazly, Amany Abdel-Fattah& Farweez, Yousra Ahmed Thabet& Elewa, Lamia Salah& Abdelmaguid Mohamed Elzankalony, Yasser& Farweez, Botheina Ahmed Thabet. 2017. Effect of Active and Passive Smoking on Retinal Nerve Fibre Layer and Ganglion Cell Complex. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1185151
Modern Language Association (MLA)
El-Shazly, Amany Abdel-Fattah…[et al.]. Effect of Active and Passive Smoking on Retinal Nerve Fibre Layer and Ganglion Cell Complex. Journal of Ophthalmology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1185151
American Medical Association (AMA)
El-Shazly, Amany Abdel-Fattah& Farweez, Yousra Ahmed Thabet& Elewa, Lamia Salah& Abdelmaguid Mohamed Elzankalony, Yasser& Farweez, Botheina Ahmed Thabet. Effect of Active and Passive Smoking on Retinal Nerve Fibre Layer and Ganglion Cell Complex. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1185151
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185151