Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor
Joint Authors
Garcia-Martin, Elena
Pablo, Luis E.
Satue, Maria
Obis, Javier
Rodrigo, Maria J.
Ara, Jose R.
Cipres, Marta
Jarauta, L.
Almarcegui, C.
Dolz, I.
Martin, J.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
To assess the capability of the vision monitor unit Monpack One of detecting visual function alterations in patients with multiple sclerosis (MS) and to evaluate the correlation between structural retinal parameters and functional measurements obtained with this device.
Methods.
Forty-eight patients with MS and 46 healthy controls were included in a cross-sectional study.
All participants underwent a complete functional evaluation of the visual pathway, which included low-contrast visual acuity (LCVA), contrast sensitivity vision (CSV), automated perimetry, multifocal visual evoked potentials (mfVEPs), and pattern electroretinogram (ERG).
All tests were performed using the vision monitor unit Monpack One (Metrovision, France), a multifunction stimulator device.
Retinal structural measurements were obtained in all subjects using Triton swept source optical coherence tomography (Topcon, Japan).
Results.
Patients with MS presented reduced low-contrast VA (p<0.001) and reduced CSV at medium (p=0.001, p=0.013) and low (p=0.001, p=0.002) spatial frequencies.
All visual field parameters were found to be altered in MS patients compared with controls (≤0.001).
Patients with MS presented lower amplitude of the P100 waveform of the mfVEP in areas corresponding to central (p<0.001), inferonasal (p=0.001), and inferotemporal (p=0.003) retina.
The pattern ERG did not show significant differences.
Significant correlations were observed between structural retinal measurements and functional parameters, especially between the inner macular areas and measurements corresponding to contrast sensitivity and perimetry indexes.
Conclusions.
Patients with MS present visual dysfunction detectable with the vision monitor unit Monpack One.
This device may be a fast and useful tool to provide a full evaluation of axonal damage in patients with multiple sclerosis.
American Psychological Association (APA)
Satue, Maria& Jarauta, L.& Obis, Javier& Cipres, Marta& Rodrigo, Maria J.& Almarcegui, C.…[et al.]. 2019. Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185322
Modern Language Association (MLA)
Satue, Maria…[et al.]. Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1185322
American Medical Association (AMA)
Satue, Maria& Jarauta, L.& Obis, Javier& Cipres, Marta& Rodrigo, Maria J.& Almarcegui, C.…[et al.]. Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185322
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185322