Holistic Approach in Designing the Personalized Bone Scaffold: The Case of Reconstruction of Large Missing Piece of Mandible Caused by Congenital Anatomic Anomaly

Joint Authors

Milovanovic, Jelena R.
Stojkovic, Milos S.
Husain, Karim N.
Korunovic, Nikola D.
Arandjelovic, Jovan

Source

Journal of Healthcare Engineering

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-23

Country of Publication

Egypt

No. of Pages

13

Main Topic

Public Health
Medicine

Abstract EN

The paper reports on the importance of applying the holistic approach in designing a personalized bone scaffold, but also all other kinds of personalized implants.

In addition, the paper attempts to point out the important aspects of the design of a PBS against which the quality of a realistic and applicable design solution should be assessed.

The holistic approach refers to the adaptation of design features of a bone scaffold to the multilateral specifics related to the particular patient, its surgical case, and curing treatment.

To ensure a successful application, five aspects of personalized bone scaffold design should be considered while it is being adapted: anatomical congruency, mechanical conformity, biochemical compatibility and biodegradability, manufacturability, and implantability.

To demonstrate the importance of applying a holistic approach in designing a personalized bone scaffold, the paper shows a case where a patient-specific scaffold aimed at the reconstruction of a large missing piece of mandible was designed.

The research resulted in a series of recommendations regarding the methods of bone geometry reconstruction and scaffold design.

The paper sheds new light on the desired mechanical properties of a personalized bone scaffold while also recommending possible design parameters for optimizing the construction according to these properties.

Finally, it recommends a possible procedure of integral production of personalized bone scaffold and bone graft.

The presented so-called holistic approach announces a new systematic process of designing a personalized bone scaffold, which, although requiring a comprehensive consideration of complex requirements, is inevitable to make the designed solution applicable.

American Psychological Association (APA)

Milovanovic, Jelena R.& Stojkovic, Milos S.& Husain, Karim N.& Korunovic, Nikola D.& Arandjelovic, Jovan. 2020. Holistic Approach in Designing the Personalized Bone Scaffold: The Case of Reconstruction of Large Missing Piece of Mandible Caused by Congenital Anatomic Anomaly. Journal of Healthcare Engineering،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1186329

Modern Language Association (MLA)

Milovanovic, Jelena R.…[et al.]. Holistic Approach in Designing the Personalized Bone Scaffold: The Case of Reconstruction of Large Missing Piece of Mandible Caused by Congenital Anatomic Anomaly. Journal of Healthcare Engineering No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1186329

American Medical Association (AMA)

Milovanovic, Jelena R.& Stojkovic, Milos S.& Husain, Karim N.& Korunovic, Nikola D.& Arandjelovic, Jovan. Holistic Approach in Designing the Personalized Bone Scaffold: The Case of Reconstruction of Large Missing Piece of Mandible Caused by Congenital Anatomic Anomaly. Journal of Healthcare Engineering. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1186329

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1186329