Toxoplasmosis in Pregnant Women and HIVAIDS Patients in Ethiopia: A Systematic Review and Meta-Analysis

Joint Authors

Gebreweld, Angesom
Feleke, Daniel Getacher
Zewde, Gashaw

Source

Journal of Parasitology Research

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-10-01

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Zoology
Diseases

Abstract EN

Background.

Although Toxoplasma gondii infection in immune-competent individuals is usually asymptomatic or causes a mild flu-like illness, it may become severe and can occasionally be fatal in immune-compromised people, such as AIDS patients or pregnant women.

Method.

Electronic English databases (Pubmed, Google Scholar, Science Direct, and Scopus), parasitology congresses, and theses of Ethiopian medical universities, were systematically searched (published or unpublished data).

Full-length articles and abstracts were collected using keywords such as Toxoplasma gondii, Toxoplasmosis, pregnant women, HIV/AIDS, and Ethiopia.

Results.

Analysis of seroprevalence estimates was pooled using a random effects meta-analysis.

Seventeen studies were included in the present systematic review and meta-analysis.

One of these studies reported seroprevalence of T.

gondii in HIV/AIDS patients and pregnant women.

In this review, a total of 4,030 individuals were included and analyzed.

The pooled prevalence of T.

gondii in this review was 81.00% (95% CI = 69.10–89.78).

Sub-group analysis showed that 2,557 pregnant women were evaluated.

In pregnant women, the pooled sero-prevalence was 71.2 (95% CI = [51.9%, 87.1%].

In HIV/AIDS patients, 1,473 individuals were evaluated and the pooled seroprevalence was 88.45 (95% CI = 80.87%–94.31%).

Conclusion.

This systematic review and meta-analysis identified a high seroprevalence of Toxoplasma infection of 81% among immunocompromised patients.

Scaling up prevention and control methods mainly strengthening educational efforts are necessary to avoid reactivation and to stop the spread of T.

gondii infection.

American Psychological Association (APA)

Feleke, Daniel Getacher& Gebreweld, Angesom& Zewde, Gashaw. 2019. Toxoplasmosis in Pregnant Women and HIVAIDS Patients in Ethiopia: A Systematic Review and Meta-Analysis. Journal of Parasitology Research،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186811

Modern Language Association (MLA)

Feleke, Daniel Getacher…[et al.]. Toxoplasmosis in Pregnant Women and HIVAIDS Patients in Ethiopia: A Systematic Review and Meta-Analysis. Journal of Parasitology Research No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1186811

American Medical Association (AMA)

Feleke, Daniel Getacher& Gebreweld, Angesom& Zewde, Gashaw. Toxoplasmosis in Pregnant Women and HIVAIDS Patients in Ethiopia: A Systematic Review and Meta-Analysis. Journal of Parasitology Research. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186811

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1186811