Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Kaposi’s sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi’s sarcoma-associated herpesvirus (KSHV).
KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS-defining malignancy.
The different forms of KS including HIV-associated KS, iatrogenic (immunosuppression-related) KS, and classical KS in elderly males suggest that immune cell dysregulation is among the key components in promoting KS development in KSHV-infected individuals.
It is therefore expected that different cell types of the immune system likely play distinct roles in promoting or inhibiting KS development.
This narrative review is focused on discussing cells of the innate and adaptive immune systems in KSHV infection and KS pathogenesis, including how these cells can be useful in the control of KSHV infection and treatment of KS.
American Psychological Association (APA)
Ngalamika, Owen& Munsaka, Sody. 2020. Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187626
Modern Language Association (MLA)
Ngalamika, Owen& Munsaka, Sody. Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma. Journal of Immunology Research No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1187626
American Medical Association (AMA)
Ngalamika, Owen& Munsaka, Sody. Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187626
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187626