Major Bleeding Events Are Stronger Predictors of Long-Term Mortality Than Coronary Events in Secondary Prevention Therapy for Ischaemic Heart Disease

Joint Authors

Maekawa, Yuichiro
Kageyama, Shigetaka
Murata, Koichiro
Nawada, Ryuzo
Onodera, Tomoya

Source

Journal of Interventional Cardiology

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-30

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Diseases

Abstract EN

Background.

Secondary prevention of ischaemic heart disease (IHD) is an important aspect of healthcare.

To improve the prognosis of and control risk factors for IHD patients, we created a unique referral system called the Shizuoka IHD patient registry.

Methods.

From 2009 to 2013, we enrolled 1240 patients; they participated in follow-up until 2018.

The risk factor target values were as follows: low-density-lipoprotein cholesterol, <100 mg/dl; glycated haemoglobin of diabetes patients, <7%; systolic blood pressure, <130 mmHg; and diastolic blood pressure, <80 mmHg (mean follow-up interval, 2001 ± 794 days).

The cumulative incidence rates were 10.8% for all-cause death (cardiac death, 1.5%), 15.7% for coronary events, and 2.6% for major bleeding.

Patients were separated into the major bleeding group (n = 32), coronary event group (n = 195), and event-free group (n = 1013) without overlapping.

Results.

We observed significant differences in age, rate antithrombotic drug use, and mortality.

A Kaplan–Meier analysis of all-cause death showed significant differences between the event-free and major bleeding groups (P=0.002) and between the coronary event and major bleeding groups (P=0.026); there was no significant difference between the event-free and coronary event groups.

Conclusion.

Major bleeding events were stronger predictors of long-term mortality than coronary events during the long-term follow-up of stable IHD.

American Psychological Association (APA)

Kageyama, Shigetaka& Murata, Koichiro& Nawada, Ryuzo& Onodera, Tomoya& Maekawa, Yuichiro. 2020. Major Bleeding Events Are Stronger Predictors of Long-Term Mortality Than Coronary Events in Secondary Prevention Therapy for Ischaemic Heart Disease. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187898

Modern Language Association (MLA)

Kageyama, Shigetaka…[et al.]. Major Bleeding Events Are Stronger Predictors of Long-Term Mortality Than Coronary Events in Secondary Prevention Therapy for Ischaemic Heart Disease. Journal of Interventional Cardiology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1187898

American Medical Association (AMA)

Kageyama, Shigetaka& Murata, Koichiro& Nawada, Ryuzo& Onodera, Tomoya& Maekawa, Yuichiro. Major Bleeding Events Are Stronger Predictors of Long-Term Mortality Than Coronary Events in Secondary Prevention Therapy for Ischaemic Heart Disease. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1187898

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1187898