The Effect of Palm Oil-Fried Street Kokor on Liver and Kidney Biomarkers of Swiss Albino Mice
Joint Authors
Fekadie, Minale
Amsalu, Hailemariam
Wondimnew, Tesaka
Mateos, Tigist
Bogale, Gesese
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Foods fried with oils at streets contain many harmful substances for health.
Locally fried foods are consumed commonly in our society, yet their health effect is not studied.
Objective.
To assess the effect of palm oil-fried street kokor on liver and kidney biomarkers of Swiss Albino mice.
Methods.
Thirty-two male and female Swiss Albino mice with the age of 10-12 weeks old were divided randomly into four groups of eight members with equal male and female subgroups.
The control group (group I) received only a standard pellet, and the experimental groups (group II, group III, and group IV) received 10%, 20%, and 30% kokor of their daily food consumption, respectively.
At the end of the 6th week, they were sacrificed by thoracoabdominal incision after anesthetizing by diethyl ether.
Blood was taken from each mouse by cardiac puncture and analyzed for liver and kidney function tests.
Result.
The serum levels of liver damage biomarkers (alanine transaminase (ALT) and aspartate transaminase (AST)) and kidney damage biomarkers (urea and creatinine) of experimental groups were increased significantly relative to the control groups (P<0.05).
Level of biochemical profiles increased as the dose of kokor increased.
Conclusions.
Palm oil-fried street kokor damaged the liver and kidney of the mice, and the damage was exacerbated as the dose of kokor increased.
American Psychological Association (APA)
Amsalu, Hailemariam& Wondimnew, Tesaka& Mateos, Tigist& Fekadie, Minale& Bogale, Gesese. 2020. The Effect of Palm Oil-Fried Street Kokor on Liver and Kidney Biomarkers of Swiss Albino Mice. Journal of Lipids،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1187924
Modern Language Association (MLA)
Amsalu, Hailemariam…[et al.]. The Effect of Palm Oil-Fried Street Kokor on Liver and Kidney Biomarkers of Swiss Albino Mice. Journal of Lipids No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1187924
American Medical Association (AMA)
Amsalu, Hailemariam& Wondimnew, Tesaka& Mateos, Tigist& Fekadie, Minale& Bogale, Gesese. The Effect of Palm Oil-Fried Street Kokor on Liver and Kidney Biomarkers of Swiss Albino Mice. Journal of Lipids. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1187924
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187924