Association of Plasma C1qTNF-Related Protein 3 (CTRP3) in Patients with Atrial Fibrillation
Joint Authors
Liu, Shuwang
Chen, Liwen
Bai, Jin
Cui, Ming
Sun, Lijie
Xu, Wei
Zhang, Yuan
Li, Lei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Atrial fibrillation (AF) is a highly prevalent cardiac arrhythmia characterized by atrial remodeling.
Complement C1q tumor necrosis factor-related protein 3 (CTRP3) is one of the adipokines associated with obesity, diabetes, and coronary heart disease.
The association between plasma CTRP3 levels and AF is uncertain.
The aim of this study was to investigate whether plasma CTRP3 concentrations were correlated with AF.
Our study included 75 AF patients who underwent catheter ablation at our hospital and 47 sinus rhythm patients to determine the difference in plasma CTRP3 concentrations.
Blood samples before the ablation were collected, and ELISA was used to measure the concentrations of CTRP3.
Plasma CTRP3 concentrations were significantly lower in AF patients compared with control group (366.9±105.2 ng/ml vs.
429.1±100.1 ng/ml, p=0.002).
In subgroup studies, patients with persistent AF had lower plasma CTRP3 concentrations than those with paroxysmal AF (328.3±83.3 ng/ml vs.
380.0±109.2 ng/ml, p=0.037).
The concentrations of plasma CTRP3 in the recurrence group after radiofrequency catheter ablation of AF were lower than those in the nonrecurrence group (337.9±77.3 ng/ml vs.
386.6±108.1 ng/ml, p=0.045).
Multivariate regression analysis revealed the independent correlation between plasma CTRP3 level and AF.
Plasma CTRP3 concentrations were correlated with the presence of AF and AF recurrence.
American Psychological Association (APA)
Chen, Liwen& Liu, Shuwang& Xu, Wei& Zhang, Yuan& Bai, Jin& Li, Lei…[et al.]. 2020. Association of Plasma C1qTNF-Related Protein 3 (CTRP3) in Patients with Atrial Fibrillation. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1192169
Modern Language Association (MLA)
Chen, Liwen…[et al.]. Association of Plasma C1qTNF-Related Protein 3 (CTRP3) in Patients with Atrial Fibrillation. Mediators of Inflammation No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1192169
American Medical Association (AMA)
Chen, Liwen& Liu, Shuwang& Xu, Wei& Zhang, Yuan& Bai, Jin& Li, Lei…[et al.]. Association of Plasma C1qTNF-Related Protein 3 (CTRP3) in Patients with Atrial Fibrillation. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1192169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192169