Lung Interstitial Macrophages: Past, Present, and Future
Joint Authors
Schyns, Joey
Bureau, Fabrice
Marichal, Thomas
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
For a long time, investigations about the lung myeloid compartment have been mainly limited to the macrophages located within the airways, that is, the well-known alveolar macrophages specialized in recycling of surfactant molecules and removal of debris.
However, a growing number of reports have highlighted the complexity of the lung myeloid compartment, which also encompass different subsets of dendritic cells, tissue monocytes, and nonalveolar macrophages, called interstitial macrophages (IM).
Recent evidence supports that, in mice, IM perform important immune functions, including the maintenance of lung homeostasis and prevention of immune-mediated allergic airway inflammation.
In this article, we describe lung IM from a historical perspective and we review current knowledge on their characteristics, ontogeny, and functions, mostly in rodents.
Finally, we emphasize some important future challenges for the field.
American Psychological Association (APA)
Schyns, Joey& Bureau, Fabrice& Marichal, Thomas. 2018. Lung Interstitial Macrophages: Past, Present, and Future. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192482
Modern Language Association (MLA)
Schyns, Joey…[et al.]. Lung Interstitial Macrophages: Past, Present, and Future. Journal of Immunology Research No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1192482
American Medical Association (AMA)
Schyns, Joey& Bureau, Fabrice& Marichal, Thomas. Lung Interstitial Macrophages: Past, Present, and Future. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192482
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192482