Analysis in Choroidal Thickness in Patients with Graves’ Ophthalmopathy Using Spectral-Domain Optical Coherence Tomography
Joint Authors
Zhang, Junqing
Yu, Nan
Zhang, Yadi
Kang, Lei
Gao, Ying
Wu, Yuan
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
The objective of the study is to observe changes in choroidal thickness (CT) in patients with Graves’ ophthalmopathy using spectral-domain optical coherence tomography (SD-OCT).
Methods.
The right eyes of 36 patients (27 females and 9 males) with Graves’ ophthalmopathy (GO) and those of 36 age-, gender-, and diopter-level-matched healthy participants were evaluated.
The patients’ data were obtained within 3 months after the onset of Graves’ disease (GD).
Thyroid hormone levels and thyroid-stimulating hormone receptor antibody (TRAb) levels were measured, and the degree of exophthalmos was measured in all patients.
Activity is measured by the clinical activity score (CAS).
A horizontal scan centered on the fovea was performed in all participants.
Five points of choroidal thickness were measured at the fovea (SFCT) and at 1500 μm nasal (N1500), 3000 μm nasal (N3000), 1500 μm temporal (T1500), and 3000 μm temporal (T3000) to the fovea.
Results.
The CT measurements obtained were (mean ± SD) 313.47 ± 100.32 μm, 279.22 ± 85.80 μm, 214.64 ± 75.52 μm, 313.19 ± 80.36 μm, and 298.14 ± 82.75 μm in patients with GO and were 256.33 ± 50.18 μm, 223.14 ± 59.61 μm, 176.69 ± 60.66 μm, 250.92 ± 52.184 μm, and 239.47 ± 60.35 μm in the control group at the foveal, N1500, N3000, T1500, and T3000 measurement points, respectively.
The CT in GO patients was significantly increased at all the points compared with the control group (P<0.05).
There was no relationship between the CT and CAS, the degree of exophthalmos, triiodothyronine (T3), tetraiodothyronine (T4), thyroid-stimulating hormone (TSH), or TRAb levels in GO.
Conclusions.
CT was found to be increased in GO patients and had poor relationship with CAS, exophthalmos, and thyroid function tests.
American Psychological Association (APA)
Yu, Nan& Zhang, Yadi& Kang, Lei& Gao, Ying& Zhang, Junqing& Wu, Yuan. 2018. Analysis in Choroidal Thickness in Patients with Graves’ Ophthalmopathy Using Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1196467
Modern Language Association (MLA)
Yu, Nan…[et al.]. Analysis in Choroidal Thickness in Patients with Graves’ Ophthalmopathy Using Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1196467
American Medical Association (AMA)
Yu, Nan& Zhang, Yadi& Kang, Lei& Gao, Ying& Zhang, Junqing& Wu, Yuan. Analysis in Choroidal Thickness in Patients with Graves’ Ophthalmopathy Using Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1196467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196467