Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer
Joint Authors
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-18
Country of Publication
Egypt
No. of Pages
11
Abstract EN
Somatic cells can be reprogrammed into a pluripotent cellular state similar to that of embryonic stem cells.
Given the significant physiological differences between the somatic and pluripotent cells, cell reprogramming is associated with a profound reorganization of the somatic phenotype at all levels.
The remodeling of mitochondrial morphology is one of these dramatic changes that somatic cells have to undertake during cell reprogramming.
Somatic cells transform their tubular and interconnected mitochondrial network to the fragmented and isolated organelles found in pluripotent stem cells early during cell reprogramming.
Accordingly, mitochondrial fission, the process whereby the mitochondria divide, plays an important role in the cell reprogramming process.
Here, we present an overview of the importance of mitochondrial fission in both cell reprogramming and cellular transformation.
American Psychological Association (APA)
Prieto, Javier& Torres, Josema. 2017. Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer. Stem Cells International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1202214
Modern Language Association (MLA)
Prieto, Javier& Torres, Josema. Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer. Stem Cells International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1202214
American Medical Association (AMA)
Prieto, Javier& Torres, Josema. Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1202214
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202214