Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke

Joint Authors

Baltar, Adriana
Piscitelli, Daniele
Marques, Déborah
Shirahige, Lívia
Monte-Silva, Kátia

Source

Neural Plasticity

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-25

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Biology
Medicine

Abstract EN

Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation.

The ability to predict an individual’s potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS therapy.

We investigated the clinical and biological characteristics which might predict tDCS plus physical therapy effects on upper limb motor recovery in chronic stroke patients.

A cohort of 80 chronic stroke individuals underwent ten to fifteen sessions of tDCS plus physical therapy.

The sensorimotor function of the upper limb was assessed by means of the upper extremity section of the Fugl-Meyer scale (UE-FM), before and after treatment.

A backward stepwise regression was used to assess the effect of age, sex, time since stroke, brain lesion side, and basal level of motor function on UE-FM improvement after treatment.

Following the intervention, UE-FM significantly improved (p<0.05), and the magnitude of the change was clinically important (mean 6.2 points, 95% CI: 5.2–7.4).

The baseline level of UE-FM was the only significant predictor (R2=0.90, F1,76=682.80, p<0.001) of tDCS response.

These findings may help to guide clinical decisions according to the profile of each patient.

Future studies should investigate whether stroke severity affects the effectiveness of tDCS combined with physical therapy.

American Psychological Association (APA)

Baltar, Adriana& Piscitelli, Daniele& Marques, Déborah& Shirahige, Lívia& Monte-Silva, Kátia. 2020. Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke. Neural Plasticity،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1202979

Modern Language Association (MLA)

Baltar, Adriana…[et al.]. Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke. Neural Plasticity No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1202979

American Medical Association (AMA)

Baltar, Adriana& Piscitelli, Daniele& Marques, Déborah& Shirahige, Lívia& Monte-Silva, Kátia. Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1202979

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1202979