Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.
Joint Authors
Campos, Jaqueline Ferreira
de Picoli Souza, Kely
Alfredo, Tamaeh Monteiro
Cardoso, Claudia Andréa Lima
Rodrigues, Allan Belarmino
Almeida-Apolonio, Adriana Araújo de
Dantas, Fabiana Gomes da Silva
Oliveira, Kelly Mari Pires de
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-28
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Ocotea minarum is a native plant from Brazil, popularly known as “canelinha” or “canela vassoura.” The objective of this study was to investigate the chemical composition of the extracts of the bark and the leaves of O.
minarum and to evaluate its antimicrobial and antioxidant activities.
The phenolic compounds, flavonoids and tanins, were quantified with the reagents Folin-Ciocalteu, aluminium chloride, and vanillin.
The chemical profile was performed by HPLC-DAD.
The minimum inhibitory concentration was evaluated by the microdilution in a broth method.
The antioxidant activity was measured by the capture of free radicals 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid).
In addition, protection against oxidative hemolysis and generation of malondialdehyde were evaluated in human erythrocytes.
The composition of the extracts included the caffeic acid, p-coumaric acid, and rosmarinic acid, besides the flavonoids quercetin and luteolin.
The EEL showed bacteriostatic action of 1000 μg/mL for all evaluated Salmonella Typhimurium, Salmonella Enteritidis, Pseudomonas aeruginosa, and Proteus mirabilis, and the EHEB had a moderate antifungal action against Candida krusei and Cryptococcus gattii (250 μg/mL).
IC50 values of 8.19 (EEL) and 4.51 μg/mL (EEB) in the assay with DPPH and 6.25 (EEL) and 2.87 μg/mL (EEB) in the assay with ABTS were obtained.
Up to the 3rd hour of oxidative hemolysis testing induced by AAPH, the EEB and EEL had a protective action, reducing the malondialdehyde.
In conclusion, the data indicate that the O.
minarum extracts can be evaluated as bioactive supplies for the development of new drugs for the prevention and treatment of diseases related to oxidative stress and microbial infections.
American Psychological Association (APA)
Rodrigues, Allan Belarmino& Almeida-Apolonio, Adriana Araújo de& Alfredo, Tamaeh Monteiro& Dantas, Fabiana Gomes da Silva& Campos, Jaqueline Ferreira& Cardoso, Claudia Andréa Lima…[et al.]. 2019. Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1204267
Modern Language Association (MLA)
Rodrigues, Allan Belarmino…[et al.]. Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1204267
American Medical Association (AMA)
Rodrigues, Allan Belarmino& Almeida-Apolonio, Adriana Araújo de& Alfredo, Tamaeh Monteiro& Dantas, Fabiana Gomes da Silva& Campos, Jaqueline Ferreira& Cardoso, Claudia Andréa Lima…[et al.]. Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1204267
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204267