Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey
Joint Authors
Selamoglu, Zeliha
Sevindik, Mustafa
Akgul, Hasan
Braidy, Nady
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Infundibulicybe geotropa (Bull.) Harmaja is an edible mushroom found in Bolu province in northwestern Turkey.
The chemical composition and bioactivity of these mushrooms has not been previously investigated.
We examined the phenolic composition, elemental content, and antioxidant and antigenotoxic effects of methanol extracts of fruiting bodies.
The phenolic compounds in the fungal samples were determined using high-performance liquid chromatography (HPLC), and element content was determined using atomic absorption spectrophotometry.
Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined using the commercially available Rel assay kit.
The antigenotoxic effects of the extract were determined using the MTT assay to assess cell viability and the alkaline single-cell gel electrophoresis assay (Comet assay).
The total phenolic content (ppm) of I.
geotropa was found to be catechin (361±2.31), clorogenic acid (553.54±5.06), and coumaric acid (9.93±0.25).
The TAS, TOS, and OSI of the extract were 1.854±0.051 mmol/L, 30.385±0.399 μmol/L, and 1.639±0.067, respectively.
The elemental levels were within “normal” range.
In HT22 mouse hippocampal neuronal cells, the extract (100 and 200 μg/ml) showed no genotoxic potential and ameliorated hydrogen peroxide- (H2O2-) induced oxidative DNA damage.
I.
geotropa may be considered a good nutrient due to its phenolic constituents and antioxidant potential.
American Psychological Association (APA)
Sevindik, Mustafa& Akgul, Hasan& Selamoglu, Zeliha& Braidy, Nady. 2020. Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1204904
Modern Language Association (MLA)
Sevindik, Mustafa…[et al.]. Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1204904
American Medical Association (AMA)
Sevindik, Mustafa& Akgul, Hasan& Selamoglu, Zeliha& Braidy, Nady. Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1204904
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204904