Role of Long Noncoding RNAs in Parkinson’s Disease: Putative Biomarkers and Therapeutic Targets
Joint Authors
Lv, Qiankun
Wang, Ziyu
Zhong, Zhen
Huang, Wei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Parkinson’s disease (PD) is a neurodegenerative disease characterized by bradykinesia, rigidity, and tremor.
Age is the main risk factor.
Long noncoding RNAs (lncRNAs) are novel RNA molecules of more than 200 nucleotides in length.
They may be involved in the regulation of many pathological processes of PD.
PD has a variety of pathophysiological mechanisms, including alpha-synuclein aggregate, mitochondrial dysfunction, oxidative stress, calcium homeostasis, axonal transport, and neuroinflammation.
Among these, the impacts of lncRNAs on the pathogenesis and progression of PD need to be highlighted.
lncRNAs may serve as putative biomarkers and therapeutic targets for the early diagnosis of PD.
This study aimed to investigate the role of lncRNAs in various pathological processes of PD and the specific lncRNAs that might be used as putative diagnostic biomarkers and therapeutic targets of PD.
American Psychological Association (APA)
Lv, Qiankun& Wang, Ziyu& Zhong, Zhen& Huang, Wei. 2020. Role of Long Noncoding RNAs in Parkinson’s Disease: Putative Biomarkers and Therapeutic Targets. Parkinson’s Disease،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1206470
Modern Language Association (MLA)
Lv, Qiankun…[et al.]. Role of Long Noncoding RNAs in Parkinson’s Disease: Putative Biomarkers and Therapeutic Targets. Parkinson’s Disease No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1206470
American Medical Association (AMA)
Lv, Qiankun& Wang, Ziyu& Zhong, Zhen& Huang, Wei. Role of Long Noncoding RNAs in Parkinson’s Disease: Putative Biomarkers and Therapeutic Targets. Parkinson’s Disease. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1206470
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206470