Validation of Parkinson’s Disease-Related Questionnaires in South Africa
Joint Authors
Faust, Irene M.
Racette, Brad A.
Nelson, Gill
Ndlovu, Ntombizodwa
Christofides, Nicola
Hlungwani, Tintswalo M.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
There are very few epidemiological studies investigating Parkinson’s disease (PD) in Africa.
The hundreds of local languages and dialects make traditional screening and clinical evaluation tools difficult to use.
Objective.
The objective of the study was to validate two commonly used PD questionnaires in an African population.
Methods.
The PD Screening Questionnaire (PDSQ) and Parkinson’s Disease Questionnaire (PDQ-39) were modified and translated into Afrikaans, Setswana, and isiZulu and administered to a sample of healthy local residents.
We assessed the internal consistencies and cluster characteristics of the questionnaires, using a Cronbach’s alpha test and exploratory factor analysis.
The questionnaires were then administered to a population-based sample of 416 research participants.
We evaluated the correlations between the questionnaires and both a timed motor task and the Unified Parkinson’s Disease Rating Scale motor subsection 3 (UPDRS3), using locally weighted scatterplot smoothing (LOWESS) regression analysis and Spearman’s rank correlation.
Results.
Both questionnaires had high overall internal consistency (Cronbach’s alpha = 0.86 and 0.95, respectively).
The modified PDQ-39 had evidence of five subscales, with Factor 1 explaining 57% and Factor 2 explaining 14%, of the variance in responses.
The PDSQ and PDQ-39 scores were correlated with the UPDRS3 score (ρ = 0.35, P<0.001; and ρ = 0.28, P<0.001, respectively).
Conclusion.
The translated PDSQ and PDQ-39 questionnaires demonstrated high internal consistency and correlations with clinical severity of parkinsonism and a timed motor task, suggesting that they are valid tools for field-based epidemiological studies.
American Psychological Association (APA)
Nelson, Gill& Ndlovu, Ntombizodwa& Christofides, Nicola& Hlungwani, Tintswalo M.& Faust, Irene M.& Racette, Brad A.. 2020. Validation of Parkinson’s Disease-Related Questionnaires in South Africa. Parkinson’s Disease،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1206496
Modern Language Association (MLA)
Nelson, Gill…[et al.]. Validation of Parkinson’s Disease-Related Questionnaires in South Africa. Parkinson’s Disease No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1206496
American Medical Association (AMA)
Nelson, Gill& Ndlovu, Ntombizodwa& Christofides, Nicola& Hlungwani, Tintswalo M.& Faust, Irene M.& Racette, Brad A.. Validation of Parkinson’s Disease-Related Questionnaires in South Africa. Parkinson’s Disease. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1206496
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206496