Chemical composition and antifungal activities of the methanol extracts of salvia multicaulis (Vahl)‎ and salvia spinosa L.

Abstract EN

exhibit antifungal activity against Alternaria alternate, Fusarium oxysporum f.sp.

lycopersici, Penicillium expansum , Sclerotium cepivorum and Botrytis cinerea.

While, S.

spinosa extract had antifungal activity against P.

expansum and B.

cinerea.

The findings provide support for the use of these plants in the search of new natural sources of bioactive compounds.The present study was carried out to determine the chemical composition and antifungal of methanol extracts derived from the aerial parts of two aromatic plants Salvia multicaulis Vahl.

and Salvia spinosa L.

(family: Lamiaceae) growing under semiarid conditions in Syria.

The aerial parts were collected, during 2016, and the extraction process was conducted with methanol (MeOH) in a Soxhlet device and analyzed using Gas Chromatography- Mass Spectrometry (GC/MS).

The antifungal activity of the methanol extracts was tested against five fungal species at concentrations of 250, 500, 750, 1000, 1250, 1500, 1750, 2000, 2500 and 3000 ppm by using poison food technique.

In total, 14 and 22 compounds were identified in the methanol extracts from the aerial parts of S.

multicaulis and S.

spinosa, respectively.

The major components in the methanol extract of S.

multicaulis were, 1,8-cineole (35.97%), trans -nerolidol (13.85%), trans-caryophyllene (11.50%), α-pinene (8.46%) and spathulenol (8.06%).

Whereas, the major components in the methanol extracts of S.

spinosa were, β-ocimene (27.23%),1,8-cineole (13.17%), linoleic acid (11.25%) β- patchoulene (12.77%), bicyclo (10.1.0) tridec-1-ene (6.73%) and camphene(5.89%).

The result indicated that S.

multicaulis extract-