التطور الطبيعي و المعدل للعيب الحاجزي البطيني المعزول عند الأطفال

Abstract EN

Background:: Ventricular septal defect (VSD) is a common congenital heart disease (CHD).

Spontaneous closure of the VSD may occur depending on the type and size of defects.

Objective: This study was carried out to determine the natural history of VSD in children.

Subjects and Methods: 832 children diagnosed with isolated VSD were prospectively studied between January 2005 and December 2011.

They had regular two dimensional (2D) echocardiography evaluations for the VSD size.

doppler color flow mapping studies were performed to define the defect anatomy, location and evolution.

Results: 832 children diagnosed with isolated Ventricular Septal Defect, the mean age at presentation was 21.5 ± 43 months, range (1 days-13 years) Most of the patients were male 487 (59%), while the commonest type of VSD was the perimembranous 599 (72%).

Spontaneous closure rate was highest in muscular VSD 110 cases (77%) and in the small sized defects 227 cases (43.3%).

Almost 278 (33.4%) of the patients had spontaneous closure, medical treatment was indicated in 341 cases (41)%.

Only 213 (25.6%) patients had surgery abroad in the entire series.

Conclusion: spontaneous closure readily occurs in small sized defects.

the frequency of spontaneous closure is very high in the first 6 month, the overall outcome of muscular VSDs was better than that of perimembranous type.

Most patients with moderate to large VSDs are confined to long term medical management.