اصطناع مشتقات فلورينية للحلقات غير المتجانسة عبر استخدام شالكون (2-استيل فلورين-بنزالدهيد)‎

Abstract EN

We have synthesized some new compounds from 2- Acetyl Fluorenyl Benzaldehyde chalcone via condensation and cyclization reactions between the chalcone and each of thiourea and urea, hydroxylamine hydrochloride and Hydrazine hydrate, these reactions afford these compounds: 3-(2- fluorenyl) 5-phenyl) pyrazoline (4), 3-(2- fluorenyl) -5- phenyl Isoxazoline (3), 4- (2- fluorenyl) 6- phenyl pyrimidinone-2 (2) and 4-(2- fluorenyl) 6-phenyl pyrimidine -2 tione (1).

In addition, 3- (2-fluorenyl) 5-phenyl isoxazole (5) was prepared via Bromination of chalcon and cyclization the later with Hydroxyl Amine hydrochloride.

Identification and determination of compounds structures were carried out by (IR, :H-NMR, 13C-NMR, MS, lC-MS) spectrum Analysis.