دراسة تأثير بعض المضادات الحيوية على بكتيريا Staphylococcus aureus و Pseudomonas aeruginosa المعزولة من أخماج الحروق و الجروح

Abstract EN

The study includes 100 isolates (67 burns & 33 wounds) from the total number of isolates , 64 isolates of Pseugomonas aeruginosa (50 burns & 14 wounds) and 36 isolates of Staphylococcus aureus (17 burns & 19 wounds)isolated from burn and wound swab, from different hospitals, in Baghdad, for the period from November 2007 to May 2008 ,which identification of these isolate by using API 20 NE and API Staph , and study antibiotics sensitivity by using Disk diffusion method towards 18 antibiotics.

Pesudomonas aeruginosa isolates showed height resistance to Azetreoname, Pipracillin, Carbencillin, Cefepime, Cefixime, Cephalexin, Ceftriaxone, Cefotixime, Ceftazidime, Trimethoprime, and Co- trimoxazole with percentage 100 %, and to Gentamicin, Tobramycin, Ciprofloxacin, Norfloxacin andImipenem with percentage (89, 79.68, 60.9, 81.25, 42.1) % respectively, While two of burns isolates showed resistance to Colisitin with percentage 3.2 % so Staphylococcus aureus showed high resistance to Methicillin and Ampicillin with Percentage 100 %, and to Cefriaxone , Augmentin, Erythromycin, Gentamicin, Tobramycin, Tetracyclin, Trimethprim, Co-trimoxazole with percentage (72.2, 86.1, 52.77, 41.66, 36.1, 50, 33.3, 30.5 ) % respectively, and less resistance to Imipenem, Rifampicin, Ciprofloxacin, Cefotaxime with percentage (22.2, 27.7, 13.88, 16.66) % respectively.

The isolates showed the same resistance towards Norfloxacin, Ofloxacin and Enoxacin with percentage 19.4 % .

All strains were sensitive to Vancomycin .

minimal inhibitory concentrations of some antibiotics were determined .

for Imipenem, the MICs values ranged between (2 – 512) μg/mL, Ciprofloxacin, (2-128) μg/mL.

Norfloxacin, (8-1024) μg/mL, Cefotaxime,( 4->1024) μg/mL, Gentamicin,( 4->1024) μg/mL