Study the beneficial activity of low level laser in experimentally induced pain in mice

Abstract EN

Low-level laser therapy (LLLT) was applied to alleviate pain with minimal adverse effects.

This study was conducted to evaluate the analgesic effects of low-level laser therapy for pain control to help in surgical and emergency cases.

The present study has demonstrated these effects experimentally on forty-five male albino mice weighing 45±5 grams.

Creation of pain in animals was done by injection of 50µl of 5% formalin into the left posterior paw.

Lifting of the paw was considered as an indicator of the pain.

All animals were divided into 3 groups 15 mice in each group.

In group A the LLLT 820nm.200mw, 48J / cm2 was focused on the affected paw for 1 min.

In group B a diode laser with same dose in group A and different time used to irradiate the injected paw continuously for 30 seconds.

The group C (control group); the laser probe was placed over the affected paw for concurrent but the apparatus was switched off.

The results demonstrated that there were significant differences between group A and B when compared with group C during the 5 minutes as well as in 10 minutes and 15 minutes.

Group A also registered a superior analgesic effect when compared with group B.

Groups of LLLT were better than those found for control one and the irradiation continuous for one minute was better than 30 seconds at 5, 10 and 15 minutes after the creation of pain.