طرق مقترحة لمعالجة مشاكل تحيز النشر في التحليل الميتي : دراسة تطبيقية

Abstract EN

Meta analysis is used to collect results from various studies to achieve high level of statistical precision unlike the estimations based on a single study.

Meta- analysis techniques depends on applying a package of statistical tools on the extant literature results to find a common relationships among these studies.

The major concern of this research is that, most of the previous studies focus on publishing large trials and significant results studies ignoring small trial studies which leads to publication bias problem, as a result it's complicated to find the confidence intervals.

The researcher focused on proposing different techniques to estimate the confidence intervals with a noticeable emphasize on publication bias of the literature with small trials to determine the confidence intervals for the mentioned studies size.

The study accomplished different results.

First, there is a publication bias regard small trials studies.

Second, the effect size of Henmi and Copas was significant.

In other words, there is a considerable effect of chemotherapy treatment on reducing the leukemia.

Third, There is a clear homogeneity of the applied methods in the analysis.

Besides to the homogeneity of the effect size regarding the suggested methods except the unrestricted weighted least squares method.