Hematological and biochemical status of βeta-thalassemia major patients in Koya city
Joint Authors
Salih, Kochar Khasro
Kakey, Ismail S.
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 33, Issue 5 (31 Oct. 2021), pp.76-84, 9 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2021-10-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Thalassemia major is a severe anemia that requires blood transfusions.
In this study, we searched into the hematological and biochemical status of βeta-thalassemia major patients in Koya.
Hematological analysis revealed severe anemia in βeta-thalassemia patients when compared to controls.
The hemoglobin levels in patients were less than 30% of that of controls.
Furthermore, patients had a significant leukocytosis compared to the controls.
Red blood cell incidences are decreased except RDW, which were Hct includes (23.8±2.9 % vs.
34.6±2.3 %), MCV (71.8±7.1 fl vs.
77.5±4.1 fl), MCH (20.2±2.4 pg vs.
23.5 ± 2.2 pg) and MCHC (30.8±0.7 g/dl vs.
30.1±1.2 g/dl), while RDW % (20.5±9.7 % vs.
14.2±2.5 %).
The linear regression analysis showed non- correlation between iron overload with RBC, WBC, and red blood cell incidences (hemoglobin (Hb), hematocrit (Hct), mean corpuscle hemoglobin (MCH), and mean corpuscle hemoglobin concentration (MCHC), while PLT count, mean corpuscular volume (MCV) and red cell distribution width (RDW) showed a significant positive correlation with iron overload.
The biochemical characteristics of the patients showed a significant increase in the levels of liver enzymatic parameters, ALP, ALT, and AST as compared to controls.
American Psychological Association (APA)
Salih, Kochar Khasro& Kakey, Ismail S.. 2021. Hematological and biochemical status of βeta-thalassemia major patients in Koya city. ZANCO Journal of Pure and Applied Sciences،Vol. 33, no. 5, pp.76-84.
https://search.emarefa.net/detail/BIM-1388092
Modern Language Association (MLA)
Salih, Kochar Khasro& Kakey, Ismail S.. Hematological and biochemical status of βeta-thalassemia major patients in Koya city. ZANCO Journal of Pure and Applied Sciences Vol. 33, no. 5 (2021), pp.76-84.
https://search.emarefa.net/detail/BIM-1388092
American Medical Association (AMA)
Salih, Kochar Khasro& Kakey, Ismail S.. Hematological and biochemical status of βeta-thalassemia major patients in Koya city. ZANCO Journal of Pure and Applied Sciences. 2021. Vol. 33, no. 5, pp.76-84.
https://search.emarefa.net/detail/BIM-1388092
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 83-84
Record ID
BIM-1388092