Comparison of misoprostol doses in termination of pregnancy in the first trimester
Other Title(s)
مقارنة بين جرعات الميزوبروستول في إنهاء الحمل في الثلث الأول من الحمل
Joint Authors
Yusuf, Ahmad Hasan
Ramadan, Lina Salman
Husaynatu, Rim Mustafa
Source
Journal of Medical and Pharmaceutical Sciences
Issue
Vol. 6, Issue 2 (30 Jun. 2022), pp.91-98, 8 p.
Publisher
Publication Date
2022-06-30
Country of Publication
Palestine (Gaza Strip)
No. of Pages
8
Main Subjects
Abstract EN
Objective: The aim of this study is to compare the efficacy of vaginal misoprostol with different doses for abortion in the first trimester.
Patients and Methods: Descriptive Comparative Study conducted for the period one year (July 2020 –July 2021) at Tishreen University Hospital in Lattakia- Syria.
The study included 80 pregnant women in the first trimester who had a therapeutic indication for termination of pregnancy after taken consent from it and her fathers, and were divided into group A was (40 women): were administrated 400 µg of vaginal misoprostol and repeated every 6 h for 48 h, and group B was (40 women): were administrated 800 µg of vaginal misoprostol repeated after 24 h.
Results: Abortion rate after the first dose in group B was higher than group A (67.5% vs.10%).
The rate of complete abortion was significantly higher in group B (72.5%) vs.
(17.5%) in group A, p= 0.0001, and mean induction- abortion interval in group B was significantly shorter than group A (13.8±3.3 vs.
29.4±5.9, p: 0.004).
There weren't significant associations between both indications and results of abortion with the number of pregnancies in the two groups (p>0.05).
Nausea was the most frequent side effect in the two groups without significant difference (p>0.05).
Conclusion: Misoprostol represents a safe and effective alternative to invasive methods for termination early intrauterine pregnancy.
American Psychological Association (APA)
Husaynatu, Rim Mustafa& Ramadan, Lina Salman& Yusuf, Ahmad Hasan. 2022. Comparison of misoprostol doses in termination of pregnancy in the first trimester. Journal of Medical and Pharmaceutical Sciences،Vol. 6, no. 2, pp.91-98.
https://search.emarefa.net/detail/BIM-1406436
Modern Language Association (MLA)
Ramadan, Lina Salman…[et al.]. Comparison of misoprostol doses in termination of pregnancy in the first trimester. Journal of Medical and Pharmaceutical Sciences Vol. 6, no. 2 (Jun. 2022), pp.91-98.
https://search.emarefa.net/detail/BIM-1406436
American Medical Association (AMA)
Husaynatu, Rim Mustafa& Ramadan, Lina Salman& Yusuf, Ahmad Hasan. Comparison of misoprostol doses in termination of pregnancy in the first trimester. Journal of Medical and Pharmaceutical Sciences. 2022. Vol. 6, no. 2, pp.91-98.
https://search.emarefa.net/detail/BIM-1406436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 97-98
Record ID
BIM-1406436