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المقارنة بين تصليب القرنية المسرع مع إزالة الظهارة و بدون إزالتها عند مرضى القرنية المخروطية
Other Title(s)
Comparison of epithelium-off versus epithelium-on accelerated corneal cross-linking in keratoconus patients
Joint Authors
عمار بسام علي
درويش، تيم رفيق
حبيب عبد اللطيف يوسف
Source
مجلة العلوم الطبية و الصيدلانية
Issue
Vol. 6, Issue 2 (30 Jun. 2022), pp.1-12, 12 p.
Publisher
Publication Date
2022-06-30
Country of Publication
Palestine (Gaza Strip)
No. of Pages
12
Main Subjects
Abstract EN
Background: Keratoconus is a slowly progressive disorder characterized by a thinning and protruding cornea.
Keratoconus leads to a significant disturbance of vision.
Corneal sclerotherapy is a photochemical reaction between the photosensitive riboflavin (vitamin B2) and ultraviolet A (UV type A), which results in the formation of free oxygen radicals that increase the bonds between collagen fibers in the corneal parenchyma, which is done in order to increase the energy of the corneal sclerotherapy.
Shortening the exposure time so that it becomes more convenient and comfortable for the patient, and corneal cross-linking has two modes: with epithelium removal and without removal.
Oobjective: Comparison of the efficacy of accelerated corneal cross-linking with and without epithelium removal in patients with progressive keratoconus.
Research materials and methods: In this prospective study, (27) eyes of (16) progressive Keratoconus patients underwent accelerated corneal collagen cross-Linking (ACXL), (12) Epithelium-off (Epi-off) and (15) Epithelium-on (Epi-on) randomly in the Ophthalmology Department in Tishreen University Hospital.
Uncorrected visual acuity (UCVA) , best corrected visual acuity(BCVA) ,spherical equivalent (SE), maximum keratometry (K max) and corneal thinnest point(CTP) for all eyes were measured before and after 1, 3, 6 and 12 months of ACXL.
Results: UCVA and BCVA improved significantly in Epi-off and Epi-on with non-significant changes between the two groups.
There were no significant changes in the K max or spherical equivalent in either of the two groups or between them during our follow-up.
There were no significant differences in the values of corneal thinnest point between the two groups or even in the Epi-on group, while we found a significant decrease in the Epi-off group after the first, then it increased during the 3, 6, and 12 months of the follow-up and reached the basic value.
Conclusion: Accelerated Corneal Collagen Cross-Linking, including Epi-off and Epi-on, shows a good efficacy and stabilization in keratoconus patients with non-statistically significant differences between the two groups at follow-up points 1, 3, 6, and 12 months after the procedure.
American Psychological Association (APA)
عمار بسام علي ودرويش، تيم رفيق وحبيب عبد اللطيف يوسف. 2022. المقارنة بين تصليب القرنية المسرع مع إزالة الظهارة و بدون إزالتها عند مرضى القرنية المخروطية. مجلة العلوم الطبية و الصيدلانية،مج. 6، ع. 2، ص ص. 1-12.
https://search.emarefa.net/detail/BIM-1406441
Modern Language Association (MLA)
عمار بسام علي....[و آخرون]. المقارنة بين تصليب القرنية المسرع مع إزالة الظهارة و بدون إزالتها عند مرضى القرنية المخروطية. مجلة العلوم الطبية و الصيدلانية مج. 6، ع. 2 (حزيران 2022)، ص ص. 1-12.
https://search.emarefa.net/detail/BIM-1406441
American Medical Association (AMA)
عمار بسام علي ودرويش، تيم رفيق وحبيب عبد اللطيف يوسف. المقارنة بين تصليب القرنية المسرع مع إزالة الظهارة و بدون إزالتها عند مرضى القرنية المخروطية. مجلة العلوم الطبية و الصيدلانية. 2022. مج. 6، ع. 2، ص ص. 1-12.
https://search.emarefa.net/detail/BIM-1406441
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 10-12
Record ID
BIM-1406441