Protective effect of Acorus calamus on kidney and liver functions in healthy mice
Author
Source
Saudi Journal of Biological Sciences
Issue
Vol. 28, Issue 5 (31 May. 2021), pp.2701-2708, 8 p.
Publisher
Publication Date
2021-05-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Abstract EN
Acorus calamus (AC), is an herbal medicine commonly used as traditional practice in pharmacological applications.
Present study initiated was evident to proof the hepatoprotective and nephroprotective activity with supporting histopathological status of kidneys and liver.
Investigation done with the 5% (w/v) of AC dissolved in tap water (50 g/l) given for 15 days compared with control tap water to 5-7 week old C57Bl/6 mice both sexes.
Renal function, liver function, biochemical and complete blood count was evaluated.
AC significantly reduced food intake, body weight, also plasma concentration of electrolytes such as Na+ , K+ , Ca2+, were reduced as the excretion of electrolytes were increased in urine, significantly increased Fluid Intake, with Urinary urea, Urinary creatinine, Glomerular Filtration Rate, creatinine clear-ance, High-density lipoproteins, Mean Corpuscular Volume.
The biochemical findings showed the hep- atoprotective and histopathological changes showed the nephroprotective nature of AC by normal structure with no necrosis.
American Psychological Association (APA)
Nasir, Umaymah. 2021. Protective effect of Acorus calamus on kidney and liver functions in healthy mice. Saudi Journal of Biological Sciences،Vol. 28, no. 5, pp.2701-2708.
https://search.emarefa.net/detail/BIM-1414496
Modern Language Association (MLA)
Nasir, Umaymah. Protective effect of Acorus calamus on kidney and liver functions in healthy mice. Saudi Journal of Biological Sciences Vol. 28, no. 5 (2021), pp.2701-2708.
https://search.emarefa.net/detail/BIM-1414496
American Medical Association (AMA)
Nasir, Umaymah. Protective effect of Acorus calamus on kidney and liver functions in healthy mice. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 5, pp.2701-2708.
https://search.emarefa.net/detail/BIM-1414496
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 2707-2708
Record ID
BIM-1414496