Adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum state, Sudan : a cross-sectional hospital study
Joint Authors
Abbas, Ala Abd Allah
Badi, Safa
Ahmad, Manhal al-Tajani
Muhammad, Sarah Muhammad al-Hasan
Jar al-Nabi, Shahd Shakir
Muhammad, Wafa Abd Allah
Ahmad, Musab
Ahmad, Muhammad Hasan
Source
Sudan Journal of Medical Sciences
Issue
Vol. 17, Issue 3 (30 Sep. 2022), pp.313-329, 17 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2022-09-30
Country of Publication
Sudan
No. of Pages
17
Main Subjects
Abstract EN
Background: Graft survival post-kidney transplantation is of paramount importance to patients and nephrologists.
Nonadherence to immunosuppressive therapy can be associated with deterioration of renal function and graft rejection.
This study aimed to evaluate the adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum, Sudan.
Methods: In this descriptive cross-sectional hospital-based survey, 277 post-kidney-transplant patients were recruited.
Data were collected using a questionnaire and analyzed using the SPSS v.23.
Our scoring method was calculated based on Morisky Medication Adherence Scale (MMAS-8) related to immunosuppressive medications and was expressed as questions in the questionnaire; every correct answer was given one mark, then the marks were gathered and their summation was expressed.
Results: Overall, 33% ,45%, and 22% of the studied participants reported high, medium, and low adherence, respectively.
The major factor for nonadherence was forgetfulness affecting 36.1% of those who did not adhere.
The cost of the immunosuppressive medications did not negatively affect any of the participants’ adherence (100%).
However, a significant association was seen between adherence and occupational status, duration of transplantation, shortage of immunosuppressants, recognizing the name of immunosuppressant, side effect, and forgetfulness (P-values = 0.002, 0.01, 0.006 , 0.000, 0.022, and 0.000, respectively).
Logistic regression analysis showed a significant association with occupational status, side effects, and forgetfulness.
Conclusion: Only one-third of the participants were classed as “highly adherent” to their immunosuppressant medications.
Factors that can affect adherence to immunosuppressant medications were occupational status, side effects, and forgetfulness.
American Psychological Association (APA)
Abbas, Ala Abd Allah& Ahmad, Manhal al-Tajani& Muhammad, Sarah Muhammad al-Hasan& Jar al-Nabi, Shahd Shakir& Muhammad, Wafa Abd Allah& Ahmad, Musab…[et al.]. 2022. Adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum state, Sudan : a cross-sectional hospital study. Sudan Journal of Medical Sciences،Vol. 17, no. 3, pp.313-329.
https://search.emarefa.net/detail/BIM-1429817
Modern Language Association (MLA)
Abbas, Ala Abd Allah…[et al.]. Adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum state, Sudan : a cross-sectional hospital study. Sudan Journal of Medical Sciences Vol. 17, no. 3 (2022), pp.313-329.
https://search.emarefa.net/detail/BIM-1429817
American Medical Association (AMA)
Abbas, Ala Abd Allah& Ahmad, Manhal al-Tajani& Muhammad, Sarah Muhammad al-Hasan& Jar al-Nabi, Shahd Shakir& Muhammad, Wafa Abd Allah& Ahmad, Musab…[et al.]. Adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum state, Sudan : a cross-sectional hospital study. Sudan Journal of Medical Sciences. 2022. Vol. 17, no. 3, pp.313-329.
https://search.emarefa.net/detail/BIM-1429817
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 326-329
Record ID
BIM-1429817