A New Statistical Trend in Medical Research : nested design

Abstract EN

is research is unlike many others in that the concept of the nested design is applied in the medical science as against thetrend in the agricultural and social sciences.

In this research, we consider a three-stage (2 × 5 × 2) nested design with the factorsbeing Hospital Centre, Days of the week and Ailments such that the days of the week are nested within the centres and theailments are nested within the days.

The replications represent the weight of twelve (12) patients selected randomly for each day in each centre which brings the total number of replications to 240.

This work being largely an illustration uses simulated data.

Analyses of variance (ANOVA) for the sum of squares across all factors and within replicates were investigated for significance.Results obtained reveal that the days and ailments are significant factors in the experiment at 5% significant level.