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دراسة فعالية و أمان كريم حمض الأزيليك 15% في علاج التهاب الجلد المثي خفيف لمتوسط الشدة في الوجه
Other Title(s)
The efficacy and safety of azelaic acid (AZA) cream 15% in the topical treatment of mild to moderate seborrheic dermatitis of the face
Joint Authors
الشوا، كندة فاروق
حمدو، سراب أيمن شيخ
Source
Issue
Vol. 37, Issue 3 (30 Sep. 2021), pp.1-11, 11 p.
Publisher
Publication Date
2021-09-30
Country of Publication
Syria
No. of Pages
11
Main Subjects
Abstract EN
Background and Aim: The aim of this study was to compare the efficacy and safety of Azelaic Acid (AZA) Cream 15%, with Ketoconazole cream 2% in adults of mild to moderate seborrheic dermatitis of the face.
Mterial and Methods: In this randomized clinical trial, 40 patients with a diagnosis of SD were enrolled.
34 patients of them completed the study and they were instructed to apply either Azelaic Acid cream 15% (18 patients) or ketoconazole cream 2% (16 patients) twice daily to the affected area of the face.
The severity of facial SD was assessed at 0,2,4,and 6 weeks of the treatment.
Secondary efficacy measures included patient assessment of adverse events and improvement percentage (IP).
Results: Statistically, ketoconazole was more effective than Azelaic acid in reducing the severity of lesions at the fourth and sixth week of treatment.
Although the decrease in erythema and pruritus was higher in the ketoconazole group at the end of the sixth week, there was no statistical significance between two groups in the decrease of papules and scales.
The rate of adverse events was similar in both groups.
Conclusions: According to our study,the two treatments were effective in the treatment of mild to moderate facial SD, but ketoconazole was more effective than Azelaic acid.
American Psychological Association (APA)
حمدو، سراب أيمن شيخ والشوا، كندة فاروق. 2021. دراسة فعالية و أمان كريم حمض الأزيليك 15% في علاج التهاب الجلد المثي خفيف لمتوسط الشدة في الوجه. مجلة جامعة دمشق للعلوم الطبية،مج. 37، ع. 3، ص ص. 1-11.
https://search.emarefa.net/detail/BIM-1431634
Modern Language Association (MLA)
حمدو، سراب أيمن شيخ والشوا، كندة فاروق. دراسة فعالية و أمان كريم حمض الأزيليك 15% في علاج التهاب الجلد المثي خفيف لمتوسط الشدة في الوجه. مجلة جامعة دمشق للعلوم الطبية مج. 37، ع. 3 (2021)، ص ص. 1-11.
https://search.emarefa.net/detail/BIM-1431634
American Medical Association (AMA)
حمدو، سراب أيمن شيخ والشوا، كندة فاروق. دراسة فعالية و أمان كريم حمض الأزيليك 15% في علاج التهاب الجلد المثي خفيف لمتوسط الشدة في الوجه. مجلة جامعة دمشق للعلوم الطبية. 2021. مج. 37، ع. 3، ص ص. 1-11.
https://search.emarefa.net/detail/BIM-1431634
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 10-11
Record ID
BIM-1431634