الترابط بين مشعر تباين توزع الكريات الحمر و درجة فعالية المرض عند مرضى الداء الروماتوئيدي
Other Title(s)
Correlation between red blood cell distribution width (rdw) and disease activity in patients with rheumatoid arthritis
Joint Authors
Source
Issue
Vol. 37, Issue 4 (31 Dec. 2021), pp.231-242, 12 p.
Publisher
Publication Date
2021-12-31
Country of Publication
Syria
No. of Pages
12
Main Subjects
Abstract EN
Background & Aim: Rheumatoid arthritis is a chronic inflammatory disease that may lead to disability due to joint deformities, so one of the priorities of treatment was to evaluate its severity and to find indicators and measurements to evaluate disease activity and remission, and several recent studies have shown a relationship between the activity of many chronic inflammatory diseases, including rheumatoid arthritis and (RDW).
There is a positive correlation between the disease activity and (RDW).
This study aims to study the relationship between (RDW) and disease activity in a sample of rheumatoid arthritis patients in University Hospitals in Damascus and to compare it with a healthy cohort.
Materials and methods: a cross-sectional/case-control study was conducted of 135 patients diagnosed with rheumatoid arthritis, and a healthy cohort of 135 people from the University Hospitals in Damascus.
(RDW) was compared between the two groups, and the value of (RDW) in patients was compared with disease activity after dividing them by using (DAS28-ESR) into four groups: remission, mild, moderate, and severe disease activity.
The data was analyzed using the statistical analysis program (SPSS) version (25) and the variable was considered statistically significant when the P-Value is less than (0.05).
Results: The average age of patients and controls at Al-maw sat hospital was (44.5±13.87) and (41.40±16.41) years, respectively(P-Value=0.249), while the average age of patients and controls at al-Assad hospital was (49.7±15.57) and (50.7±9.78) years, respectively (P-Value=0.657).
(RDW) was statistically significant higher in al Assad hospital patient group (16.6±1.78%) compared to al Assad control Group (13.55±0.51%) P-Value≤0.0001.
In addition, (RDW) of al Mowasat hospital patients (15.6±2.54%) was significantly higher than al Mowasat hospital controls (13.55±1.08%) and P-Value≤0.0001.
The study has shown a positive correlation between (RDW) and (DAS28-ESR).
Conclusion: (RDW) is significantly higher in rheumatoid arthritis patients compared to healthy people, and it is possible to use (RDW) as a disease activity predictor in rheumatoid arthritis in the presence or absence of anemia.
American Psychological Association (APA)
أغيد عزيز وقدسي، ميسون. 2021. الترابط بين مشعر تباين توزع الكريات الحمر و درجة فعالية المرض عند مرضى الداء الروماتوئيدي. مجلة جامعة دمشق للعلوم الطبية،مج. 37، ع. 4، ص ص. 231-242.
https://search.emarefa.net/detail/BIM-1435929
Modern Language Association (MLA)
أغيد عزيز وقدسي، ميسون. الترابط بين مشعر تباين توزع الكريات الحمر و درجة فعالية المرض عند مرضى الداء الروماتوئيدي. مجلة جامعة دمشق للعلوم الطبية مج. 37، ع. 4 (2021)، ص ص. 231-242.
https://search.emarefa.net/detail/BIM-1435929
American Medical Association (AMA)
أغيد عزيز وقدسي، ميسون. الترابط بين مشعر تباين توزع الكريات الحمر و درجة فعالية المرض عند مرضى الداء الروماتوئيدي. مجلة جامعة دمشق للعلوم الطبية. 2021. مج. 37، ع. 4، ص ص. 231-242.
https://search.emarefa.net/detail/BIM-1435929
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 242
Record ID
BIM-1435929