القيمة الإنذارية لنقص صوديوم المصل عند مرضى متلازمة الإكليلية الحادة

Abstract EN

Background & Aim: Hyponatremia is a common electrolyte disorder, and is associated with adverse outcomes in patients with acute coronary syndrome (ACS).

This study was designed to determine the relationship between hyponatremia at admission and in-hospital outcomes in patients with acute coronary syndrome.

Materials and Methods: This was a cross - sectional study conducted at Al-Assad and Al- Mouassat University Hospitals, Damascus, during the period between March 2020 - March 2021.

Plasma sodium concentration was obtained in all patients at admission and analyzed as hyponatremia versus non-hyponatremia.

The relationships between hyponatremia and in-hospital mortality', arrhythmia, and heart failure was assessed.

Results: Of 144 patients with ACS, 25 (17.4%) patients had hyponatremia on presentation (sodium <135 meq/L).

Patients with hyponatremia had higher rates of in-hospital arrhythmia (16% vs.

2.5%, p=0.004), heart failure (32% vs.

12.6%, p=0.016), and mortality (24% vs.

7.6%, p=0.014) In multivariate logistic regression, hy ponatremia was independently correlated with in-hospital arrhythmia (OR: 7.36, 95% Cl: 1.5-35.3, p=0.021), heart failure (OR: 3.26, 95% Cl: 1.2- 8.86, p=0.02), and mortality (OR: 3.86, 95% Cl: 1.23- 12, p=0.02).Conclusion: Hyponatremia is independently associated with in-hospital adverse outcomes in patients with acute coronary syndrome.