مقارنة حساب تركيز الصميم البروتيني B مع معايرته بالمصل لدى عينة من السوريين الأصحاء و المصحابين بأمراض القلب الإقفارية

Abstract EN

Introduction: Apolipoprotein B (ApoB) is one of the most important predictive indicators of cardiovascular disease, because it plays the main role by introducing cholesterol into the subendothelial layer of arteries and inducing atherosclerosis, the main cause of cardiac ischemia.

Aim of the study: Comparison the values of calculated ApoB with direct titration in serum, which is somewhat costly.

Methods: a case-control study, (total 200), 100 patients suffer from ischemic heart disease and 100 healthy persons, Participants' data were taken, then laboratory tests were done creatinine, albumin, glucose, cholesterol, triacylglycerol, HDL-C, CRP, ApoB and LDL-C , ApoB were calculated, then results were studied statistically.

Results: The correlation of calculated and measured ApoB was direct strong, and regarding of accuracy and predictability for ischemic heart disease, and correlation with ischemic heart disease risk factors, they were similar.

Conclusion: The study showed that there is an agreement between calculated and measured values for Apo B, and recommends a wider study to be routinely calculated, for its advantages.