تقييم الفعالية المضادة للأكسدة و تحديد محتوى الفينولات الكلي لنبات القرصعنة المنتشر في سورية

Abstract EN

Eryngium creticum is widespread in Syria and it has diverse traditional uses, and since many acute and chronic diseases are mediated by oxidative stress, our study aimed to evaluate the antioxidant activity (AA) and determine the total phenolics (TP) of E.

creticum.

The aerial parts of E.

creticum were extracted by reflux using each of water and ethanol 80% separately.

The AA was evaluated by measuring the DPPH• free radical scavenging activity, both extracts showed high AA, with higher AA in the ethanolic extract (IC50=0.088 mg/mL) than in the aqueous extract (IC50=0.096 mg/mL) compared to Gallic Acid as positive control (IC50=1.763 μg/mL).

TP was determined using PholinCiocalteau Method, it was 32.63, 30.91 mg GAE/g E.

creticum powder in ethanolic and aqueous extracts respectively.

These results show that E.

creticum is a good source of antioxidant compounds and it may be used in prevention of diseases linked to oxidative stress.