تقصي الفعالية الحيوية (الفعالية الكاسحة للجذور الحرة و الفعالية على بعض أنزيمات الهضم في الزجاج)‎ لثلاثة أنواع من نبات العليق

Abstract EN

One of the aims of treating diabetes and obesity is to reduce the rate at which sugars and fats are absorbed from the digestive system.

In this study, the phenolic content, free radical scavenging activity, and the inhibitory activity of the digestive enzymes α-amylase, α-glucosidase, and lipase were determined for the methanolic extracts of Rubus sanctus, Rubus hedycarpus, and Rubus collinus harvested in spring and autumn.

The extract of Rubus sanctus harvested in autumn with the highest amount of phenolic content (195 mg(GAE)/g) exhibited the highest antioxidant activity (IC50=41 µg/ml), and the strongest inhibitory activity toward digestive enzymes, α-amylase (IC50=112 µg/ml), α-glucosidase (IC50=178 µg/ml), and lipase (IC50=72 µg/ml).

It was observed that the extracts harvested in autumn of each species contained a higher phenolic content, a higher antioxidant activity and a higher inhibitory activity on the digestive enzymes than the extracts obtained in spring .